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IL1A Protein

IL1A Spezies: Human Wirt: Escherichia coli (E. coli) > 97 % by SDS-PAGE and HPLC analyses. Active
Produktnummer ABIN988013
  • Target Alle IL1A Proteine anzeigen
    IL1A (Interleukin 1 alpha (IL1A))
    Biologische Aktivität
    Active
    Spezies
    • 22
    • 13
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Quelle
    • 44
    • 13
    • 12
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Sequenz
    SAPFSFLSNV KYNFMRIIKY EFILNDALNQ SIIRANDQYL TAAALHNLDE AVKFDMGAYK SSKDDAKITV ILRISKTQLY VTAQDEDQPV LLKEMPEIPK TITGSETNLL FFWETHGTKN YFTSVAHPNL FIATKQDYWV CLAGGPPSIT DFQILENQ
    Produktmerkmale
    Fully biologically active when compared to standard. The ED50 as determined by the dose-dependant stimulation of mouse D10S cells is less than 0.001 ng/ml, corresponding to aof 1 x 109 IU/mg
    Reinheit
    > 97 % by SDS-PAGE and HPLC analyses.
    Endotoxin-Niveau
    Level Less than 1EU/µg of rHuIL-1alpha as determined by LAL method
    Top Product
    Discover our top product IL1A Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at
    Lagerung
    4 °C
  • Target
    IL1A (Interleukin 1 alpha (IL1A))
    Andere Bezeichnung
    Interleukin-1 alpha (IL-1alpha) (IL1A Produkte)
    Hintergrund
    IL-1 alpha is a non-secreted proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1alpha and IL-1beta binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1beta is a secreted cytokine, IL-1alpha is predominantly a cell-associated cytokine. Synonym: Interleukin-1 alpha ( IL-1alpha) , Human. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in PBS, pH 7.4.
    Molekulargewicht
    Approximately 18.0 kDa, a single non-glycosylated polypeptide chain containing 159 amino acids.
    Pathways
    NF-kappaB Signalweg, Autophagie, Cancer Immune Checkpoints
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