IL1A Protein
Kurzübersicht für IL1A Protein (ABIN935582)
Target
Alle IL1A Proteine anzeigenProtein-Typ
Biologische Aktivität
Spezies
Quelle
Reinheit
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Sequenz
- MAPHSFQNNL RYKLIRIVKQ EFIMNDSLNQ NIYVDMDRIH LKAASLNDLQ LEVKFDMYAY SSGGDSKYPV TLKVSNTQLF VSAQGEDKPV LLKEIPETPK LITGSETDLI FFWEKINSKN YFTSAAFPEL LIATKEQSQV HLARGLPSMI DFQIS
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Produktmerkmale
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Purified recombinant Human IL1 alpha protein
Expression System: E.coli
Bioactivity: The ED50 as determined by the dose-dependent proliferation of Mouse D10S cells is 2 x 10^8 units/mg. -
Endotoxin-Niveau
- < 0.1 ng per µg (1 EU/µg).
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Buffer
- Supplied as a lyophilized powder.
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- RT/-20 °C
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- IL1A (Interleukin 1 alpha (IL1A))
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Andere Bezeichnung
- IL1 alpha
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Hintergrund
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IL1a is a non-secreted proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL1a and IL1beta binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL2 release, B-cell maturation and proliferation, mitogenic FGFlike activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells.
Alternative Names: Leukocyte Endogenous Mediator protein, Lymphocyte-activating factor protein, IL-1 protein, Interleukin 1 alpha protein, MCF protein, Mononuclear Cell Factor protein, IL 1 protein, IL1, IL-1 alpha protein, EP protein, LEM protein, Endogenous Pyrogen protein, Hematopoietin-1 protein, LAF protein, IL-1, IL 1 -
Molekulargewicht
- 17.7 kDa
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Pathways
- NF-kappaB Signalweg, Autophagie, Cancer Immune Checkpoints
Target
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