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IL-11 Protein

Dieses Recombinant IL-11-Protein wird in Escherichia coli (E. coli) exprimiert.
Produktnummer ABIN935547

Kurzübersicht für IL-11 Protein (ABIN935547)

Target

Alle IL-11 (IL11) Proteine anzeigen
IL-11 (IL11) (Interleukin 11 (IL11))

Protein-Typ

Recombinant

Biologische Aktivität

Active

Spezies

  • 19
  • 11
  • 2
  • 2
Human

Quelle

  • 15
  • 8
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Escherichia coli (E. coli)

Reinheit

> 98 % pure
  • Sequenz

    MPGPPPGPPR VSPDPRAELD STVLLTRSLL ADTRQLAAQL RDKFPADGDH NLDSLPTLAM SAGALGALQL PGVLTRLRAD LLSYLRHVQW LRRAGGSSLK TLEPELGTLQ ARLDRLLRRL QLLMSRLALP QPPPDPPAPP LAPPSSAWGG IRAAHAILGG LHLTLDWAVR GLLLLKTRL

    Produktmerkmale

    Purified recombinant Human IL11 protein
    Expression System: E.coli
    Bioactivity: The ED50 was determined by the dose-dependent stimulation of the proliferation of Mouse T11 cells is ? 2.0 ng/mL, corresponding to a specific activity of ? 5 x 10^5 units/mg.

    Endotoxin-Niveau

    < 0.1 ng per µg (1 EU/µg) of IL-11.
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  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Buffer

    Supplied as a lyophilized powder.

    Handhabung

    Avoid repeated freeze/thaw cycles.

    Lagerung

    RT/-20 °C
  • Target

    IL-11 (IL11) (Interleukin 11 (IL11))

    Andere Bezeichnung

    IL11

    Hintergrund

    IL11 is a multifunctional cytokine produced by stromal cells such as fibroblasts, epithelial cells and osteoclasts. It is expressed in a wide variety of tissues including thymus, lung, bone, connective tissue and central nervous system. IL11 plays an important regulatory role in hematopoiesis by stimulating growth of myeloid, erythroid and megakaryocyte progenitor cells. It also regulates bone metabolism, inhibits production of proinflammatory cytokines and protects against gastromucosal injury.
    Alternative Names: IL 11 protein, IL 11, IL-11 protein, AGIF protein, Interleukin 11 protein, IL-11, Adipogenesis inhibitory factor protein, IL-11 protein, IL11

    Molekulargewicht

    19.1 kDa

    Pathways

    JAK-STAT Signalweg, Negative Regulation of Hormone Secretion
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