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IL-3 Protein

Dieses Recombinant IL-3-Protein wird in Escherichia coli (E. coli) exprimiert.
Produktnummer ABIN935490

Kurzübersicht für IL-3 Protein (ABIN935490)

Target

Alle IL-3 Proteine anzeigen
IL-3 (Interleukin 3 (IL-3))

Protein-Typ

Recombinant

Biologische Aktivität

Active

Spezies

  • 23
  • 18
  • 6
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Quelle

  • 34
  • 7
  • 6
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Escherichia coli (E. coli)

Reinheit

> 98 % pure
  • Sequenz

    APMTQTTSLK TSWVNCSNMI DEIITHLKQP PLPLLDFNNL NGEDQDILME NNLRRPNLEA FNRAVKSLQN ASAIESILKN LLPCLPLATA APTRHPIHIK DGDWNEFRRK LTFYLKTLEN AQAQQTTLSL AIF

    Produktmerkmale

    Purified recombinant Human IL3 protein
    Expression System: E.coli
    Bioactivity: The ED50 as determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is ? 0.1 ng/mL, corresponding to a specific activity of ? 1 x 10^7 units/mg.

    Endotoxin-Niveau

    < 0.1 ng per µg (1 EU/µg).
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  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Reconstitute in water to a concentration of 0.1 - 1.0 mg/mL.

    Buffer

    Supplied lyophilized with no additives.

    Konservierungsmittel

    Without preservative

    Handhabung

    Avoid repeated freeze/thaw cycles.

    Lagerung

    RT/-20 °C
  • Target

    IL-3 (Interleukin 3 (IL-3))

    Andere Bezeichnung

    IL3

    Hintergrund

    IL3 is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells and eosinophils, IL3 enhances thrombopoieses, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL3 may have additional immunoregulatory roles. Many of the IL3 activities depend upon co-stimulation with other cytokines.
    Alternative Names: IL-3 protein, Multi-CSF protein, Interleukin 3 protein, HCGF protein, IL-3, IL 3, IL-3 protein, IL 3 protein, Mast cell growth factor protein, MCGF protein, P-cell stimulation factor protein, IL3

    Molekulargewicht

    15 kDa

    Pathways

    JAK-STAT Signalweg, Regulation of Carbohydrate Metabolic Process, Autophagie
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