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IL1A Protein

IL1A Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant > 98 % pure Active
Produktnummer ABIN935467
  • Target Alle IL1A Proteine anzeigen
    IL1A (Interleukin 1 alpha (IL1A))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Spezies
    • 18
    • 13
    • 8
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Maus
    Quelle
    • 40
    • 13
    • 12
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Sequenz
    SAPYTYQSDL RYKLMKLVRQ KFVMNDSLNQ TIYQDVDKHY LSTTWLNDLQ QEVKFDMYAY SSGGDDSKYP VTLKISDSQL FVSAQGEDQP VLLKELPETP KLITGSETDL IFFWKSINSK NYFTSAAYPE LFIATKEQSR VHLARGLPSM TDFQIS
    Produktmerkmale
    Purified recombinant Mouse IL1 alpha protein
    Expression System: E.coli
    Bioactivity: The ED50 as determined by the dose-dependent stimulation of Mouse D10S cells is 5 x 10^8 units/mg.
    Reinheit
    > 98 % pure
    Endotoxin-Niveau
    < 0.1 ng per µg (1 EU/µg).
    Top Product
    Discover our top product IL1A Protein
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Reconstitute in water to a concentration of 0.1-1.0 mg/mL.
    Buffer
    Lyophilized from 5 mM tris, pH 8.0.
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Lagerung
    RT/-20 °C
  • Target
    IL1A (Interleukin 1 alpha (IL1A))
    Andere Bezeichnung
    IL1 alpha (IL1A Produkte)
    Synonyme
    IL-1A Protein, IL1 Protein, IL1-ALPHA Protein, IL1F1 Protein, IL-6 Protein, Il-1a Protein, IL-1 alpha Protein, IL-1alpha Protein, L1A Protein, interleukin 1 alpha Protein, interleukin 6 Protein, IL1A Protein, IL6 Protein, Il1a Protein
    Hintergrund
    IL1a is a non-secreted proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL1a and IL1beta binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL2 release, B-cell maturation and proliferation, mitogenic FGFlike activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL1beta is a secreted cytokine, IL1a is predominantly a cell-associated cytokine.
    Alternative Names: Hematopoietin-1 protein, IL 1 protein, MCF protein, LAF protein, Lymphocyte-activating factor protein, IL 1, Leukocyte Endogenous Mediator protein, IL-1 alpha protein, Mononuclear Cell Factor protein, Endogenous Pyrogen protein, Interleukin 1 alpha protein, LEM protein, EP protein, IL1, IL-1 protein, IL-1
    Molekulargewicht
    17.9 kDa
    Pathways
    NF-kappaB Signalweg, Autophagie, Cancer Immune Checkpoints
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