IL-6 Receptor Protein (AA 20-358, Subunit alpha)

Produktnummer ABIN7937427

Dieses Recombinant IL-6 Receptor-Protein wird in Insect cells (Sf21) exprimiert.

Kurzübersicht für IL-6 Receptor Protein (AA 20-358, Subunit alpha) (ABIN7937427)

Target: IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: Insect cells (Sf21)

Reinheit: > 97 % by SDS-PAGE analyses.

Produktdetails

Proteineigenschaft: AA 20-358, Subunit alpha

Verwendungszweck: Recombinant Human Interleukin-6 Receptor Subunit Alpha

Sequenz: Leu20-Asp358,

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 1 EU/ug of rHuIL-6 Ralpha as determined by LAL method.

Biological Activity Comment: Measured by its ability to enhance the IL-6 activity on M1 mouse myeloid leukemia cells. The ED50 for this effect is 5-15 ng/ml.

Anwendungsinformationen

Kommentare:

Apparent molecular mass of 45-50 kDa in SDS-PAGE under reducing conditions, a single glycosylated polypeptide protein consisting of 339 amino acids.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from 0.2 um filtered concentrated solution in PBS.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. -12 months from date of receipt, -20 to -70 °C as supplied. -1 month, 2 to 8 °C under sterile conditions after reconstitution. -3 months, -20 to -70 °C under sterile conditions after reconstitution.

Haltbarkeit: 12 months

Antigendetails

Target: IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

Andere Bezeichnung: Interleukin-6 Receptor

Molekulargewicht: 50 kDa

Pathways: JAK-STAT Signalweg, Autophagie, Growth Factor Binding, Cancer Immune Checkpoints