LIF Protein
Kurzübersicht für LIF Protein (ABIN7937415)
Target
Alle LIF Proteine anzeigenProtein-Typ
Biologische Aktivität
Spezies
Quelle
Reinheit
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Verwendungszweck
- Recombinant Murine Leukemia Inhibitory Factor
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Sequenz
- SPLPITPVNA TCAIRHPCHG NLMNQIKNQL AQLNGSANAL FISYYTAQGE PFPNNVEKLC APNMTDFPSF HGNGTEKTKL VELYRMVAYL SASLTNITRD QKVLNPTAVS LQVKLNATID VMRGLLSNVL CRLCNKYRVG HVDVPPVPDH SDKEAFQRKK LGCQLLGTYK QVISVVVQAF
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Sterilität
- 0.2 μm filtered
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Endotoxin-Niveau
- Less than 1 EU/ug of rMuLIF as determined by LAL method.
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Biological Activity Comment
- Fully biologically active when compared to standard. The specific activity is determined by inducing differentiation of murine M1 myeloid leukemic cells. The minimum detectable concentration of rMuLIF in this assay is 0.01 ng/ml. The specific activity of > 1.0 x108 IU/mg, where 50 units is defined as the amount of rMuLIF required to induce differentiation in 50 % of the M1 colonies in 1 ml agar cultures.
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Kommentare
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Approximately 19.9 kDa, a single non-glycosylated polypeptide chain containing 180 amino acids.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Buffer
- Lyophilized from a 0.2 um filtered concentrated solution in 20 mM PB, pH 7.4, with 0.02 % TWEEN 20.
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Lagerung
- 4 °C,-20 °C,-80 °C
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Informationen zur Lagerung
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.
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Haltbarkeit
- 12 months
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- LIF (Leukemia Inhibitory Factor (LIF))
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Andere Bezeichnung
- Leukemia Inhibitory Factor
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Molekulargewicht
- 19.9 kDa
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Gen-ID
- 16878
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UniProt
- P09056
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Pathways
- JAK-STAT Signalweg, Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Stem Cell Maintenance, Growth Factor Binding
Target
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