IL1A Protein
Kurzübersicht für IL1A Protein (ABIN7849706)
Target
Alle IL1A Proteine anzeigenProtein-Typ
Spezies
Quelle
Applikation
Reinheit
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Verwendungszweck
- Recombinant Human IL-1a Protein
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Sterilität
- 0.2 μm filtered
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Endotoxin-Niveau
- <0.01 EU/μg by LAL test
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Dissolve the lyophilized protein in distilled water(It is not recommended to reconstitute to a concentration<100 μg/mL.)
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Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, pH 7.5.
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Lagerung
- 4 °C,-20 °C,-80 °C
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Informationen zur Lagerung
- Ship at 4°C.Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.
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- IL1A (Interleukin 1 alpha (IL1A))
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Andere Bezeichnung
- IL-1a
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Hintergrund
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Synonyms: IL1A, IL-1A, IL1, IL1-ALPHA, IL1F1, interleukin 1 alpha, IL-1 alpha, IL-1α
Description: Recombinant human IL-1a is produced by the E.coli system, with the target gene encoding Ser113-Ala271 expressed.
Background: Interleukin-1 alpha (IL-1 alpha) also known as hematopoietin 1 is a cytokine of the interleukin 1 family that in humans is encoded by the IL1A gene.In general, Interleukin 1 is responsible for the production of inflammation, as well as the promotion of fever and sepsis. IL-1α inhibitors are being developed to interrupt those processes and treat diseases.IL-1α is produced mainly by activated macrophages, as well as neutrophils, epithelial cells, and endothelial cells. It possesses metabolic, physiological, haematopoietic activities, and plays one of the central roles in the regulation of the immune responses. It binds to the interleukin-1 receptor. It is on the pathway that activates tumor necrosis factor-alpha.
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UniProt
- P01583
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Pathways
- NF-kappaB Signalweg, Autophagie, Cancer Immune Checkpoints
Target
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