IL12B Protein (AA 23-335) (His tag)

Produktnummer ABIN7607461

Produktdetails

Target: IL12B (Interleukin 12 beta (IL12B))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Proteineigenschaft: AA 23-335

Spezies: Maus

Quelle: Mammalian Cells

Aufreinigungstag / Konjugat: Dieses IL12B Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS), Western Blotting (WB), Immunogen (Imm), ELISA, Activity Assay (AcA)

Verwendungszweck: Recombinant Mouse IL12B/IL-12 p40/NKSF2 Protein, C-His (Active)

Reinheit: >90 % as determined by SDS-PAGE.

Endotoxin-Niveau: <0.1 EU/μg of the protein by the LAL method.

Biological Activity Comment: Measured by its ability to inhibit IL-23 induced IL-17 secretion by mouse splenocytes. The ED50 for this effect is 3-18 ng/mL.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from a solution in PBS pH 7.4, 5 % Trehalose, 5 % Mannitol.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.

Haltbarkeit: 12 months

Antigendetails

Target: IL12B (Interleukin 12 beta (IL12B))

Andere Bezeichnung: IL-12 subunit p40 (IL12B Produkte)

Hintergrund: IL-12 subunit p40, IL12B, Interleukin-12 subunit beta, IL-12B, CLMF p40, NKSF2, NK cell stimulatory factor chain 2, Cytotoxic lymphocyte maturation factor 40 kDa subunit

UniProt: P43432

Pathways: JAK-STAT Signalweg, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation