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Oncostatin M Protein (OSM) (His tag)

Recombinant Oncostatin M-Protein exprimiert in HEK-293 Cells.
Produktnummer ABIN7536079

Kurzübersicht für Oncostatin M Protein (OSM) (His tag) (ABIN7536079)

Target

Alle Oncostatin M (OSM) Proteine anzeigen
Oncostatin M (OSM)

Protein-Typ

Recombinant

Spezies

  • 25
  • 6
  • 4
  • 3
  • 1
  • 1
Maus

Quelle

  • 21
  • 12
  • 1
  • 1
  • 1
  • 1
  • 1
HEK-293 Cells

Reinheit

> 97 % by SDS-PAGE.
  • Aufreinigungstag / Konjugat

    Dieses Oncostatin M Protein ist gelabelt mit His tag.

    Verwendungszweck

    Recombinant Mouse Oncostatin-M/OSM Protein

    Sequenz

    MQTRLLRTLL SLTLSLLILS MALANRGCSN SSSQLLSQLQ NQANLTGNTE SLLEPYIRLQ NLNTPDLRAA CTQHSVAFPS EDTLRQLSKP HFLSTVYTTL DRVLYQLDAL RQKFLKTPAF PKLDSARHNI LGIRNNVFCM ARLLNHSLEI PEPTQTDSGA SRSTTTPDVF NTKIGSCGFL WGYHRFMGSV GRVFREWDDG STRSRR

    Spezifität

    Met 1-Arg 206

    Sterilität

    0.22 μm filtered

    Endotoxin-Niveau

    <0.1EU/μg
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  • Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

    Buffer

    Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
  • Target

    Oncostatin M (OSM)

    Andere Bezeichnung

    Oncostatin-M/OSM

    Hintergrund

    Description: OSM is a pleiotropic cytokine that initiates its biological activities by binding to specific cell surface receptors. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIFR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration.

    Name: OncoM,OSM

    Gen-ID

    18413

    UniProt

    P53347

    Pathways

    JAK-STAT Signalweg, Negative Regulation of Hormone Secretion
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