Oncostatin M Protein (OSM) (His tag)
Kurzübersicht für Oncostatin M Protein (OSM) (His tag) (ABIN7536079)
Target
Alle Oncostatin M (OSM) Proteine anzeigenProtein-Typ
Spezies
Quelle
Reinheit
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Aufreinigungstag / Konjugat
- Dieses Oncostatin M Protein ist gelabelt mit His tag.
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Verwendungszweck
- Recombinant Mouse Oncostatin-M/OSM Protein
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Sequenz
- MQTRLLRTLL SLTLSLLILS MALANRGCSN SSSQLLSQLQ NQANLTGNTE SLLEPYIRLQ NLNTPDLRAA CTQHSVAFPS EDTLRQLSKP HFLSTVYTTL DRVLYQLDAL RQKFLKTPAF PKLDSARHNI LGIRNNVFCM ARLLNHSLEI PEPTQTDSGA SRSTTTPDVF NTKIGSCGFL WGYHRFMGSV GRVFREWDDG STRSRR
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Spezifität
- Met 1-Arg 206
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Sterilität
- 0.22 μm filtered
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Endotoxin-Niveau
- <0.1EU/μg
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
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Buffer
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
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- Oncostatin M (OSM)
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Andere Bezeichnung
- Oncostatin-M/OSM
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Hintergrund
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Description: OSM is a pleiotropic cytokine that initiates its biological activities by binding to specific cell surface receptors. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIFR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration.
Name: OncoM,OSM
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Gen-ID
- 18413
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UniProt
- P53347
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Pathways
- JAK-STAT Signalweg, Negative Regulation of Hormone Secretion
Target
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