BDNF Protein (AA 129-247)

Produktnummer ABIN7504243

Dieses Recombinant BDNF-Protein wird in Escherichia coli (E. coli) exprimiert.

Kurzübersicht für BDNF Protein (AA 129-247) (ABIN7504243)

Target: BDNF (Brain-Derived Neurotrophic Factor (BDNF))

Protein-Typ: Recombinant

Spezies: Human, Ratte, Maus

Quelle: Escherichia coli (E. coli)

Reinheit: > 95 % as determined by Tris-Bis PAGE

Produktdetails

Proteineigenschaft: AA 129-247

Verwendungszweck: Human/Murine/Rat BDNF Protein

Sequenz: His129-Arg247

Produktmerkmale: Recombinant Human/Murine/Rat BDNF Protein is expressed from E.coli without tagIt contains His129-Arg247.

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 0.01 EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: BDNF (Brain-Derived Neurotrophic Factor (BDNF))

Andere Bezeichnung: BDNF

Hintergrund: The brain-derived neurotrophic factor (BDNF) is a secretory growth factor that promotes neuronal proliferation and survival, synaptic plasticity and long-term potentiation in the central nervous system. Brain-derived neurotrophic factor biosynthesis and secretion are chrono-topically regulated processes at the cellular level, accounting for specific localizations and functions.

Molekulargewicht: 13.51 kDa. The protein migrates to 15-19 kDa based on Tris-Bis PAGE result.

UniProt: P23560-1

Pathways: RTK Signalweg, Synaptic Membrane, Feeding Behaviour, Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity