BDNF Protein

Produktnummer ABIN7488780

Recombinant BDNF-Protein exprimiert in HEK-293 Cells.

Kurzübersicht für BDNF Protein (ABIN7488780)

Target: BDNF (Brain-Derived Neurotrophic Factor (BDNF))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Reinheit: 95 %

Güteklasse: Premium grade

Produktdetails

Verwendungszweck: Human BDNF / Abrineurin Protein, premium grade

Sequenz: His 129 - Arg 247

Produktmerkmale: Human BDNF, premium grade is expressed from human 293 cells (HEK293). It contains AA His 129 - Arg 247 (Accession # P23560-1).

Endotoxin-Niveau: 0.01 EU per μg

Anwendungsinformationen

Kommentare:

This protein carries no "tag". () The protein has a calculated MW of 13.5 kDa. The protein migrates as 15-17 kDa and 19 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: PBS, pH 7.4

Lagerung: -20 °C

Informationen zur Lagerung: -20°C

Antigendetails

Target: BDNF (Brain-Derived Neurotrophic Factor (BDNF))

Andere Bezeichnung: BDNF

Hintergrund: Brain-derived neurotrophic factor (BDNF) along with nerve growth factor (NGF), neurotrophin-3 (NT-3), and neurotrophin-4/5 (NT-4/5) are members of the neurotrophin family of trophic factors. The neurotrophins play essential roles in the development, survival, and function of a wide range of neurons in both the peripheral and central nervous systems. The neurotrophins interact with two cell surface receptors, the low affinity P75 receptor and the Trk family of high affinity tyrosine kinase receptors. NGF preferentially binds TrkA, BDNF and NT4/5 bind TrkB, and NT-3 binds TrkC (and TrkA to a lesser extent).

Molekulargewicht: 13.5 kDa

Pathways: RTK Signalweg, Synaptic Membrane, Feeding Behaviour, Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity