IL-3 Protein (His tag)
Kurzübersicht für IL-3 Protein (His tag) (ABIN7447933)
Target
Alle IL-3 Proteine anzeigenProtein-Typ
Spezies
Quelle
Reinheit
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Aufreinigungstag / Konjugat
- Dieses IL-3 Protein ist gelabelt mit His tag.
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Verwendungszweck
- Cynomolgus IL-3 Protein, His Tag
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Sequenz
- Ala 20 -Gln 143
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Produktmerkmale
- Cynomolgus IL-3, His Tag is expressed from human 293 cells (HEK293). It contains AA Ala 20 -Gln 143 (Accession # G7P877-1).
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Endotoxin-Niveau
- 1.0 EU per μg
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Interleukin 3 (IL-3) (AA 20-152) protein (His-Avi Tag)
IL-3 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 3 (IL-3) (AA 20-143) protein (His tag)IL-3 Spezies: Cynomolgus Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 3 (IL-3) (AA 20-152) protein (His-Avi Tag,Biotin)IL-3 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 3 (IL-3) protein (His tag)IL-3 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by reducing SDS-PAGE.
Interleukin 3 (IL-3) (AA 27-166) protein (Fc Tag)IL-3 Spezies: Maus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 3 (IL-3) (AA 33-166) (Active) proteinIL-3 Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant > 95 % by SDS-PAGE analysis. Active
Interleukin 3 (IL-3) (AA 20-152) (Active) proteinIL-3 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % as analyzed by SDS-PAGE and HPLC. Active
Interleukin 3 (IL-3) protein (His tag)IL-3 Spezies: Maus Wirt: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Interleukin 3 (IL-3) (AA 1-152) protein (GST tag)IL-3 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP
Interleukin 3 (IL-3) (AA 20-152) (Active) protein (His tag)IL-3 Spezies: Human Wirt: Baculovirus infected Insect Cells Recombinant > 90 % by SDS - PAGE SDS Active
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Kommentare
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This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 15.9 kDa. The protein migrates as 18-27 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Buffer
- PBS, pH 7.4
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C
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- IL-3 (Interleukin 3 (IL-3))
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Andere Bezeichnung
- IL-3
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Hintergrund
- Synonyms:IL3,MCGF,MGC79398,MGC79399,MULTI-CSF,Interleukin-3,Description:Interleukin 3 is also known as IL-3, is a protein that in humans is encoded by the IL3 gene. Interleukin-3 (IL-3) is an interleukin, a type of biological signal (cytokine) that can improve the body's natural response to disease as part of the immune system. It acts by binding to the interleukin-3 receptor. The IL-3 receptor is a heterodimer of the IL-3 specific α-chain and the common β-chain, βc, which is also used by GM-CSF and IL-5. [3] Binding of IL-3 can also involve substitution of the βc by a βIL-3-chain that appears to be specific for IL-3 . Binding of IL-3 to its cognate receptor(s) induces activation of Jak2, phosphorylation of multiple Stats, and the PI3K/Akt pathway. IL-3 may play an important role in the development of airway inflammation associated with asthma. The human IL-3 gene encodes a protein 152 amino acids long, and the naturally occurring IL-3 is glycosylated. The human IL-3 gene is located on chromosome 5, only 9 kilobases from the GM-CSF gene, and its function is quite similar to GM-CSF.
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Molekulargewicht
- 15.9 kDa
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Pathways
- JAK-STAT Signalweg, Regulation of Carbohydrate Metabolic Process, Autophagie
Target
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