GAS6 Protein (AA 31-637) (His tag)

Produktnummer ABIN7274696

Produktdetails

Target: GAS6 (Growth Arrest-Specific 6 (GAS6))

Protein-Typ: Recombinant

Proteineigenschaft: AA 31-637

Spezies: Cynomolgus

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses GAS6 Protein ist gelabelt mit His tag.

Verwendungszweck: Cynomolgus GAS6 Protein

Sequenz: Ala31-Ala637

Produktmerkmale: Recombinant Cynomolgus GAS6 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala31-Ala637.

Reinheit: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Biological Activity Comment: Immobilized Cynomolgus GAS6, His Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Anti-Gas6 Antibody, hFc Tag with the EC50 of 36.2ng/ml determined by ELISA. The affinity constant of 1.70 nM as determined in SPR assay (Biacore T200). See testing image for detail.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: GAS6 (Growth Arrest-Specific 6 (GAS6))

Andere Bezeichnung: GAS6 (GAS6 Produkte)

Synonyme: fj34a12 Protein, zgc:63860 Protein, wu:fj34a12 Protein, MGC68463 Protein, gas6 Protein, MGC83872 Protein, GAS6 Protein, Gas-6 Protein, AXLLG Protein, AXSF Protein, growth arrest specific 6 Protein, growth arrest-specific 6 Protein, growth arrest specific 6 L homeolog Protein, growth arrest specific 6 S homeolog Protein, GAS6 Protein, gas6 Protein, gas6.L Protein, gas6.S Protein, Gas6 Protein

Hintergrund: Growth arrest-specific 6, also known as Gas6, is a human gene encoding the Gas6 protein, which was originally found to be upregulated in growth-arrested fibroblasts. Gas6 is a member of the vitamin K-dependent family of proteins expressed in many human tissues and regulates several biological processes in cells, including proliferation, survival and migration, by binding to its receptors Tyro3, Axl and Mer (TAM).

Molekulargewicht: 68.55 kDa. Due to glycosylation, the protein migrates to 69-74 kDa based on Tris-Bis PAGE result.

UniProt: A0A2K5VGX7

Pathways: RTK Signalweg, Carbohydrate Homeostasis, Production of Molecular Mediator of Immune Response