IL-11 Protein (Fc Tag)

Produktnummer ABIN7320821

Dieses Recombinant IL-11-Protein wird in Human Cells produziert.

Kurzübersicht für IL-11 Protein (Fc Tag) (ABIN7320821)

Target: IL-11 (IL11) (Interleukin 11 (IL11))

Protein-Typ: Recombinant

Spezies: Maus

Quelle: Human Cells

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Produktdetails

Aufreinigungstag / Konjugat: Dieses IL-11 Protein ist gelabelt mit Fc Tag.

Verwendungszweck: Recombinant Mouse Interleukin-11/IL-11 Protein (Fc Tag)

Sequenz: Pro22-Leu199

Produktmerkmale: Recombinant Mouse Interleukin-11 is produced by our Mammalian expression system and the target gene encoding Pro22-Leu199 is expressed with a Fc tag at the C-terminus.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: IL-11 (IL11) (Interleukin 11 (IL11))

Andere Bezeichnung: Interleukin-11/IL-11

Hintergrund:

Background: Interleukin-11(IL-11) is a secreted protein and belongs to the IL-6 superfamily. IL-11 has been demonstrated to improve platelet recovery after chemotherapy-induced thrombocytopenia, induceacute phase proteins, modulate antigen-antibody responses, participate in the regulation of bone cellproliferation and differentiation and could be use as a therapeutic for osteoporosis. IL-11 stimulates the growth of certain lymphocytes and, in the murine model, stimulates an increase in the cortical thickness and strength of long bones. In addition to having lymphopoietic/hematopoietic and osteotrophic properties, it has functions in many other tissues, including the brain, gut, testis and bone.

Synonym: Interleukin-11,Il11,IL-11

Molekulargewicht: 46.3 kDa

UniProt: P47873

Pathways: JAK-STAT Signalweg, Negative Regulation of Hormone Secretion