Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

BDNF Protein

Dieses Recombinant BDNF-Protein wird in Escherichia coli (E. coli) produziert.
Produktnummer ABIN7319738

Kurzübersicht für BDNF Protein (ABIN7319738)

Target

Alle BDNF Proteine anzeigen
BDNF (Brain-Derived Neurotrophic Factor (BDNF))

Protein-Typ

Recombinant

Biologische Aktivität

Active

Spezies

  • 22
  • 7
  • 6
  • 5
  • 5
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Ratte, Maus

Quelle

  • 33
  • 17
  • 3
  • 2
  • 1
  • 1
Escherichia coli (E. coli)

Reinheit

> 95 % as determined by reducing SDS-PAGE.
  • Verwendungszweck

    Recombinant Human/Mouse/Rat BDNF Protein (Active)

    Sequenz

    His129-Arg247

    Produktmerkmale

    Recombinant Human/Mouse/Rat BDNF is produced by our E.coli expression system and the target gene encoding His129-Arg247 is expressed.

    Endotoxin-Niveau

    < 1.0 EU per μg as determined by the LAL method.

    Biological Activity Comment

    Immobilized Human BDNF at 2ug/mll(100 μl/well) can bind Human TrkB-His(Cat: PKSH033579). The ED50 of Human BDNF is 2.82 ug/ml .
  • Möchten Sie weitere Optionen für dieses Protein ?

    !
    Entdecken Sie unsere vordefinierten maßgeschneiderten Proteine und Proteinservices!

    Ihr Projekt erfordert weitere Anpassungen? Kontaktieren Sie uns und entdecken Sie unsere maßgeschneiderten Proteinlösungen

  • Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 250 mM NaCl, pH 7.2.

    Lagerung

    4 °C,-20 °C,-80 °C

    Informationen zur Lagerung

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    BDNF (Brain-Derived Neurotrophic Factor (BDNF))

    Andere Bezeichnung

    BDNF

    Hintergrund

    Background: Brain-Derived Neurotrophic Factor (BDNF) is a member of the neurotrophin family. Along with other structurally related neurotrophic factors NGF, NT-3 and NT-4, BDNF binds with high affinity to the TrkB kinase receptor. It also binds with the LNGFR (for low-affinity nerve growth factor receptor, also known as p75). BDNF promotes the survival, growth and differentiation of neurons. It serves as a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. BDNF expression is altered in neurodegenerative disorders such as Parkinson',s and Alzheimer',s disease.

    Synonym: Brain-Derived Neurotrophic Factor, BDNF, Abrineurin

    Molekulargewicht

    13 kDa

    UniProt

    P23560

    Pathways

    RTK Signalweg, Synaptic Membrane, Feeding Behaviour, Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity
Sie sind hier:
Chat with us!