IL-8 Protein (AA 28-99) (Biotin)
Kurzübersicht für IL-8 Protein (AA 28-99) (Biotin) (ABIN6952239)
Target
Alle IL-8 (IL8) Proteine anzeigenProtein-Typ
Biologische Aktivität
Spezies
Quelle
Applikation
Reinheit
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Proteineigenschaft
- AA 28-99
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Aufreinigungstag / Konjugat
- Dieses IL-8 Protein ist gelabelt mit Biotin.
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Sequenz
- SAKELRCQCI KTYSKPFHPK FIKELRVIES GPHCANTEII VKLSDGRELC LDPKENWVQR VVEKFLKRAE NS
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Produktmerkmale
- Biotininylated Recombinant Human CXCL8 (IL-8)
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Endotoxin-Niveau
- <0.01 EU per 1μg of the protein by the LAL method
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Biological Activity Comment
- EC50 = 0.5-1 nM determined by Migration Assay in cells expressing recombinant CXCR1
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Interleukin 8 (IL8) (AA 28-99) protein (His tag)
IL8 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 8 (IL8) (AA 28-99) (Active) protein (His tag,AVI tag,Biotin)IL8 Spezies: Human Wirt: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Interleukin 8 (IL8) (AA 26-167) protein (His-IF2DI Tag)IL8 Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Interleukin 8 (IL8) (AA 28-99) (Active) proteinIL8 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant CMA Active
Interleukin 8 (IL8) (AA 1-99) protein (GST tag)IL8 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP
Interleukin 8 (IL8) (AA 28-99) protein (Fc Tag)IL8 Spezies: Human Wirt: HEK-293 Cells Recombinant > 90 % as determined by reducing SDS-PAGE.
Interleukin 8 (IL8) (AA 28-99) (Active) protein (Fc Tag)IL8 Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Interleukin 8 (IL8) (AA 23-101), (full length) protein (His tag)IL8 Spezies: Hund Wirt: Hefe Recombinant > 90 % ELISA
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Spin tube prior to resuspending. Recommended at 100 μg/mL in sterile water
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
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12 months from date of receipt, -20 to -70 °C as supplied.
Suggest to use immediately after reconstitution
1 month at -20 to -70 °C under sterile conditions after reconstitution. -
Haltbarkeit
- 12 months
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- IL-8 (IL8) (Interleukin 8 (IL8))
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Andere Bezeichnung
- CXCL8 (IL-8)
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Hintergrund
- Interleukin 8 (IL-8 /CXCL8) is secreted primarily by macrophages and monocytes. It is one of the key mediators for inflammatory responses. IL-8 is a strong chemotractant for neutrophils and monocytes promoting activation of these cells by binding to two cell surface receptors, CXCR1 and CXCR2. It is also a strong angiogenic agent and is considered to play a role in the pathogenesis of bronchiolitis.
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Molekulargewicht
- 10.803 kDa
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UniProt
- P10145
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Pathways
- TLR Signalweg, Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Hepatitis C, Autophagie
Target
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