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Interleukin 13 Receptor, alpha 1 (IL13RA1) (AA 26-340) protein (Fc Tag) Protein

IL13RA1 Spezies: Maus Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Produktnummer ABIN2181338
$253.00
Zzgl. Versandkosten $45.00
Lieferung in 2 bis 3 Werktagen
  • Target Alle IL13 Receptor alpha 1 (IL13RA1) Proteine anzeigen
    IL13 Receptor alpha 1 (IL13RA1)
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 26-340
    Spezies
    • 13
    • 6
    • 1
    Maus
    Quelle
    • 6
    • 4
    • 4
    • 2
    • 2
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses IL13 Receptor alpha 1 Protein ist gelabelt mit Fc Tag.
    Sequenz
    AA 26-340
    Produktmerkmale
    This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 62.7 kDa. The protein migrates as 67-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
    Reinheit
    >95 % as determined by SDS-PAGE.
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    Less than 1.0 EU per μg by the LAL method.
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    Tris with Glycine, Arginine and NaCl,  pH 7.5
    Handhabung
    Please avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
  • Target
    IL13 Receptor alpha 1 (IL13RA1)
    Andere Bezeichnung
    IL-13 R alpha 1 (IL13RA1 Produkte)
    Synonyme
    CD213A2, CT19, IL-13R, IL13BP, CD213A1, IL-13Ra, NR4, AI882074, CD213a1, IL-13r[a], Il13ra, IL13RA1, il-13ra1, si:ch211-150g2.2, interleukin 13 receptor subunit alpha 2, interleukin 13 receptor subunit alpha 1, interleukin 13 receptor, alpha 1, interleukin 13 receptor, alpha 1-like, IL13RA2, IL13RA1, Il13ra1, il13ra1, LOC100360218
    Hintergrund
    Interleukin 13 receptor, alpha 1 is also known as IL13RA1, NR4 and CD213A1 (cluster of differentiation 213A1), The IL13 Rα1 cDNA encodes a 427 amino acid (aa) residue precursor protein with a putative 21 aa residue signal peptide, a 324 aa residue extracellular domain, a 23 aa residue transmembrane region and a 59 aa residue cytoplasmic tail. Human and mouseIL13Rα1 share 76 % aa sequence identity. IL13RA1 is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4.
    Molekulargewicht
    62.7 kDa
    NCBI Accession
    NP_598751
    Pathways
    JAK-STAT Signalweg, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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