Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

Oncostatin M Protein (OSM) (AA 24-206)

OSM Spezies: Maus Wirt: HEK-293T Cells Recombinant > 95 % as analyzed by SDS-PAGE and HPLC. Active
Produktnummer ABIN2018306
  • Target Alle Oncostatin M (OSM) Proteine anzeigen
    Oncostatin M (OSM)
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Proteineigenschaft
    AA 24-206
    Spezies
    • 26
    • 4
    • 4
    • 3
    • 1
    • 1
    Maus
    Quelle
    • 21
    • 12
    • 1
    • 1
    • 1
    • 1
    HEK-293T Cells
    Produktmerkmale
    ED50 < 0.4 ng/mL, measured in a cell proliferation assay using NIH-3T3 cells.
    Reinheit
    > 95 % as analyzed by SDS-PAGE and HPLC.
    Endotoxin-Niveau
    < 0.2 EU/μg, determined by LAL method.
    Top Product
    Discover our top product OSM Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Reconstituted in ddH2O or PBS at 100 μg/mL.
    Buffer
    Lyophilized after extensive dialysis against PBS.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Lyophilized recombinant Murine Oncostatin-M remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Murine Oncostatin-M should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
    Haltbarkeit
    6 months
  • Target
    Oncostatin M (OSM)
    Andere Bezeichnung
    Oncostatin-M (OSM) (OSM Produkte)
    Hintergrund
    Oncostatin-M, also known as OSM, is a growth regulator belonging to the interleukin-6 group of cytokines. It is expressed mainly by monocytes, activated T cells and Kaposi's sarcoma cells. OSM signals through two types of receptors, one is composed of gp130 and LIFR, and the other is composed of gp130 and OSMR. OSM regulates IL-6, G-CSF and GM-CSF production, and thus is involved in hematopoiesis, neurogenesis and osteogenesis. OSM displays both stimulatory and inhibitory effects, so its categorization as pro-inflammatory or anti-inflammatory cytokine is still controversial.
    Synonyms: OSM
    Molekulargewicht
    10-40 kDa, observed by reducing SDS-PAGE.
    UniProt
    P53347
    Pathways
    JAK-STAT Signalweg, Negative Regulation of Hormone Secretion
Sie sind hier:
Kundenservice