IL-5 Protein (AA 20-132)
Kurzübersicht für IL-5 Protein (AA 20-132) (ABIN2018127)
Target
Alle IL-5 (IL5) Proteine anzeigenProtein-Typ
Biologische Aktivität
Spezies
Quelle
Reinheit
-
-
Proteineigenschaft
- AA 20-132
-
Produktmerkmale
- ED50 < 0.4 ng/mL, measured by a cell proliferation assay using TF-1 Cells, corresponding to a specific activity of > 2.5x 10^6 units/mg.
-
Endotoxin-Niveau
- < 0.2 EU/μg, determined by LAL method.
-
-
Möchten Sie weitere Optionen für dieses Protein ?
!Entdecken Sie unsere vordefinierten maßgeschneiderten Proteine und Proteinservices!Ihr Projekt erfordert weitere Anpassungen? Kontaktieren Sie uns und entdecken Sie unsere maßgeschneiderten Proteinlösungen
-
-
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Lyophilized
-
Rekonstitution
- Reconstituted in ddH2O at 100 μg/mL.
-
Buffer
- Lyophilized after extensive dialysis against 20 mM Tris, pH 8.5.
-
Lagerung
- -80 °C
-
Informationen zur Lagerung
- Lyophilized recombinant rat Interleukin-5 (rrIL-5) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rrIL-5 should be stable up to 2 weeks at 4 °C or up to 3 months at -20 °C.
-
Haltbarkeit
- 6 months
-
-
- IL-5 (IL5) (Interleukin 5 (IL5))
-
Andere Bezeichnung
- Interleukin-5 (IL-5)
-
Hintergrund
-
Interleukin-5 (IL-5), produced by mast cells, T cells and eosinophils, is responsible for the activities attributed to eosinophil differentiating factor, B cell growth factor II and T cell-replacing factor (TRF). It can increase production and mobilization of eosinophils and CD34+ progenitors from the bone marrow. IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. IL-5 also promotes differentiation of basophils and primes them for histamine and leukotriene release.Recombinant rat Interleukin-5 (rrIL-5) produced in E. coli is a disulfide-linked homodimer containing two non-glycosylated polypeptide chains of 113 amino acids each. A fully biologically active molecule, rrIL-5 has a molecular mass of 26.0 kDa analyzed by non-reducing SDS-PAGE.
Synonyms: EDF, BCDFII, TRF -
Molekulargewicht
- 26.0 kDa, observed by non-reducing SDS-PAGE.
-
UniProt
- Q08125
-
Pathways
- JAK-STAT Signalweg, Positive Regulation of Peptide Hormone Secretion, Production of Molecular Mediator of Immune Response, Feeding Behaviour
Target
-