IL1A Protein (AA 116-270)
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- Target Alle IL1A Proteine anzeigen
- IL1A (Interleukin 1 alpha (IL1A))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
- Proteineigenschaft
- AA 116-270
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Spezies
- Ratte
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Quelle
- CHO Cells
- Produktmerkmale
- ED50 <5 pg/mL, measured in a proliferation assay using D10S cells.
- Reinheit
- > 95 % as analyzed by SDS-PAGE.
- Endotoxin-Niveau
- < 0.2 EU/μg, determined by LAL method.
- Top Product
- Discover our top product IL1A Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
- Buffer
- Lyophilized after extensive dialysis against PBS.
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Lyophilized recombinant Rat Interleukin-1 alpha remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, Rat Interleukin-1 alpha should be stable up to 1 week at 4°C or up to 2 months at -20°C.
- Haltbarkeit
- 6 months
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- Target
- IL1A (Interleukin 1 alpha (IL1A))
- Andere Bezeichnung
- Interleukin-1alpha (IL-1alpha) (IL1A Produkte)
- Hintergrund
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Interleukin-1 alpha (IL-1α), is produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1alpha and IL-1beta bind to the same receptor and have similar if not identical biological properties. These cytokines have a broad range of activities including stimulation of thymocyte proliferation via IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity, and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1beta is a secreted cytokine, IL-1alpha is predominantly a cell-associated cytokine.
Synonyms: Hematopoietin-1, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF) - Molekulargewicht
- 17-22 kDa, observed by reducing SDS-PAGE.
- UniProt
- P16598
- Pathways
- NF-kappaB Signalweg, Autophagie, Cancer Immune Checkpoints
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