IL1A Protein (AA 116-270)
Kurzübersicht für IL1A Protein (AA 116-270) (ABIN2018084)
Target
Alle IL1A Proteine anzeigenProtein-Typ
Biologische Aktivität
Spezies
Quelle
Reinheit
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Proteineigenschaft
- AA 116-270
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Produktmerkmale
- ED50 <5 pg/mL, measured in a proliferation assay using D10S cells.
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Endotoxin-Niveau
- < 0.2 EU/μg, determined by LAL method.
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Interleukin 1 alpha (IL1A) (Active) protein
IL1A Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Interleukin 1 alpha (IL1A) (AA 113-271) protein (His tag)IL1A Spezies: Cynomolgus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 1 alpha (IL1A) (AA 113-271) proteinIL1A Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 1 alpha (IL1A) (AA 113-271) protein (Fc Tag)IL1A Spezies: Human Wirt: HEK-293 Cells Recombinant The purity of the protein is greater than 90 % as determined by SDS-PAGE and Coomassie blue staining.
Interleukin 1 alpha (IL1A) (AA 115-270) protein (His tag)IL1A Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Interleukin 1 alpha (IL1A) proteinIL1A Spezies: Ratte Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE
Interleukin 1 alpha (IL1A) (AA 113-271) protein (His tag)IL1A Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90% by SDS-PAGE SDS
Interleukin 1 alpha (IL1A) (AA 1-271) protein (GST tag)IL1A Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP
Interleukin 1 alpha (IL1A) (AA 172-271) protein (GST tag)IL1A Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP
Interleukin 1 alpha (IL1A) proteinIL1A Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
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Buffer
- Lyophilized after extensive dialysis against PBS.
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Lagerung
- -80 °C
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Informationen zur Lagerung
- Lyophilized recombinant Rat Interleukin-1 alpha remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, Rat Interleukin-1 alpha should be stable up to 1 week at 4°C or up to 2 months at -20°C.
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Haltbarkeit
- 6 months
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- IL1A (Interleukin 1 alpha (IL1A))
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Andere Bezeichnung
- Interleukin-1alpha (IL-1alpha)
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Hintergrund
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Interleukin-1 alpha (IL-1α), is produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1alpha and IL-1beta bind to the same receptor and have similar if not identical biological properties. These cytokines have a broad range of activities including stimulation of thymocyte proliferation via IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity, and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1beta is a secreted cytokine, IL-1alpha is predominantly a cell-associated cytokine.
Synonyms: Hematopoietin-1, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF) -
Molekulargewicht
- 17-22 kDa, observed by reducing SDS-PAGE.
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UniProt
- P16598
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Pathways
- NF-kappaB Signalweg, Autophagie, Cancer Immune Checkpoints
Target
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