IL-11 Protein (AA 23-199)
Kurzübersicht für IL-11 Protein (AA 23-199) (ABIN2018055)
Target
Alle IL-11 (IL11) Proteine anzeigenProtein-Typ
Biologische Aktivität
Spezies
Quelle
Reinheit
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Proteineigenschaft
- AA 23-199
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Produktmerkmale
- ED50 < 3 ng/mL, measured in a cell proliferation assay using T11 cells.
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Endotoxin-Niveau
- < 0.2 EU/μg, determined by LAL method.
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Interleukin 11 (IL11) (AA 22-199) protein (His tag)
IL11 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 11 (IL11) (AA 22-199) protein (His tag)IL11 Spezies: Cynomolgus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 11 (IL11) (AA 22-199) (Active) protein (His tag)IL11 Spezies: Human Wirt: Escherichia coli (E. coli) > 90 % AcA, CC Active
Interleukin 11 (IL11) (Active) proteinIL11 Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Interleukin 11 (IL11) protein (Fc Tag)IL11 Spezies: Maus Wirt: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Interleukin 11 (IL11) (AA 22-199) protein (His tag)IL11 Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Interleukin 11 (IL11) (AA 1-199) protein (GST tag)IL11 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP
Interleukin 11 (IL11) (AA 22-199) protein (Fc Tag)IL11 Spezies: Human Wirt: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Interleukin 11 (IL11) proteinIL11 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant 95,00% SDS
Interleukin 11 (IL11) (AA 22-199) (Active) protein (His tag)IL11 Spezies: Human Wirt: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
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Buffer
- Lyophilized after extensive dialysis against PBS.
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Lagerung
- -80 °C
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Informationen zur Lagerung
- Lyophilized recombinant Murine Interleukin-11 (IL-11) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Murine Interleukin-11 (IL-11) should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
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Haltbarkeit
- 6 months
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- IL-11 (IL11) (Interleukin 11 (IL11))
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Andere Bezeichnung
- Interleukin-11(IL-11)
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Hintergrund
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Interleukin-11 (IL-11) is a pleiotropic cytokine that was originally detected in the conditioned medium of an IL-1alpha-stimulated primate bone marrow stromal cell line (PU-34) as a mitogen for the IL-6-responsive mouse plasmacytoma cell line T11. IL-11 contains no cysteine residues or potential glycosylation sites. IL-11 has multiple effects on both hematopoietic and nonhematopoietic cells. Many of the biological effects described for IL-11 overlap those for IL-6. In vitro, IL-11 can synergize with IL-3, IL-4 and SCF to shorten the G0 period of early hematopoietic progenitors. IL-11 also enhances the IL-3-dependent megakaryocyte colony formation. IL-11 has been found to stimulate the T cell dependent development of specific immunoglobulin-secreting B cell.
Synonyms: IL-11 -
Molekulargewicht
- 21 kDa, observed by reducing SDS-PAGE.
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UniProt
- P47873
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Pathways
- JAK-STAT Signalweg, Negative Regulation of Hormone Secretion
Target
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