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IL-3 Protein (AA 20-152)

Recombinant IL-3-Protein exprimiert in CHO Cells.
Produktnummer ABIN2018017

Kurzübersicht für IL-3 Protein (AA 20-152) (ABIN2018017)

Target

Alle IL-3 Proteine anzeigen
IL-3 (Interleukin 3 (IL-3))

Protein-Typ

Recombinant

Biologische Aktivität

Active

Spezies

  • 23
  • 16
  • 5
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Quelle

  • 31
  • 6
  • 6
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
CHO Cells

Reinheit

> 95 % as analyzed by SDS-PAGE and HPLC.
  • Proteineigenschaft

    AA 20-152

    Produktmerkmale

    ED50 < 0.1 ng/mL, measured in a cell proliferation assay using TF-1 cells, corresponding to a specific activity of > 1x10^7 units/mg.

    Endotoxin-Niveau

    < 0.2 EU/μg, determined by LAL method.
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  • Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Reconstituted in ddH2O or PBS at 100 μg/mL.

    Buffer

    Lyophilized after extensive dialysis against PBS.

    Lagerung

    -80 °C

    Informationen zur Lagerung

    Lyophilized recombinant human Interlerkin 3 (IL-3) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rhIL-3 should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.

    Haltbarkeit

    6 months
  • Target

    IL-3 (Interleukin 3 (IL-3))

    Hintergrund

    Interleukin-3 (IL-3) is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells and eosinophils, IL-3 enhances thrombopoieses, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL-3 may have additional immunoregulatory roles. Many of the IL-3 activities depend upon co-stimulation with other cytokines. IL-3 is species-specific, variably glycosylated cytokine.Recombinant human interleukin 3 expressed in CHO cells is glycosylated protein with molecular weight range from 17 to 30 kDa shown in non-reducing SDS-PAGE.
    Synonyms: MCGF (Mast cell growth factor), Multi-CSF, HCGF, P-cell stimulation factor

    Molekulargewicht

    17-30 kDa, observed by non-reducing SDS-PAGE.

    UniProt

    Q6GS87

    Pathways

    JAK-STAT Signalweg, Regulation of Carbohydrate Metabolic Process, Autophagie
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