EGF Protein (AA 974-1026)
Kurzübersicht für EGF Protein (AA 974-1026) (ABIN2017760)
Target
Alle EGF Proteine anzeigenProtein-Typ
Biologische Aktivität
Spezies
Quelle
Reinheit
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Proteineigenschaft
- AA 974-1026
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Produktmerkmale
- ED50 < 0.1 ng/mL, measured in a cell proliferation assay using 3T3 cells.
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Endotoxin-Niveau
- < 0.2 EU/μg, determined by LAL method.
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Epidermal Growth Factor (EGF) (AA 971-1023) protein
EGF Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Epidermal Growth Factor (EGF) (Active) proteinEGF Spezies: Human Wirt: Escherichia coli (E. coli) > 95 % as determined by (a) Analysis by SEC-HPLC (b) Analysis by reducing and non-reducing SDS-PAGE Silver Stained gel Active
Epidermal Growth Factor (EGF) (AA 977-1029) protein (Fc Tag)EGF Spezies: Maus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Epidermal Growth Factor (EGF) (AA 971-1023) (Active) protein (Fc Tag)EGF Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Epidermal Growth Factor (EGF) (Active) proteinEGF Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Epidermal Growth Factor (EGF) (AA 971-1023) (Active) proteinEGF Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA Active
Epidermal Growth Factor (EGF) (AA 974-1026) (Active) protein (His tag)EGF Spezies: Ratte Wirt: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA Active
Epidermal Growth Factor (EGF) (AA 926-1025) protein (GST tag)EGF Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP
Epidermal Growth Factor (EGF) (AA 977-1029) (Active) protein (His tag)EGF Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant > 95% by SDS-PAGE SDS, AcA Active
Epidermal Growth Factor (EGF) proteinEGF Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant 97,00% SDS
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
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Buffer
- Lyophilized after extensive dialysis against PBS.
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Lagerung
- -80 °C
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Informationen zur Lagerung
- Lyophilized recombinant Rat Epidermal Growth Factor remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Rat Epidermal Growth Factor should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
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Haltbarkeit
- 6 months
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- EGF (Epidermal Growth Factor (EGF))
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Hintergrund
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Epidermal Growth Factor, a low-molecular-weight polypeptide, is the founding member of the EGF-family of proteins. It can be found in platelets, macrophages, urine, saliva, etc. EGF acts by binding with high affinity to the Epidermal Growth Factor Receptor (EGFR) and stimulating downstream protein tyrosine kinase activity. This signal transduction cascade results in increased intracellular calcium levels and increased rates of glycolysis and protein synthesis. EGF stimulates the growth of many epidermal and epithelial tissues. Pharmaceutical drugs designed to inhibit EGFR have been used to treat certain types of cancer.
Synonyms: Epidermal Growth Factor, Urogastrone, URG -
Molekulargewicht
- 6 kDa, observed by reducing SDS-PAGE.
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UniProt
- P07522
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Pathways
- NF-kappaB Signalweg, RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Protein targeting to Nucleus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation
Target
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