BDNF Protein (AA 129-247)

Produktnummer ABIN2017673

Dieses Recombinant BDNF-Protein wird in CHO Cells produziert.

Kurzübersicht für BDNF Protein (AA 129-247) (ABIN2017673)

Target: BDNF (Brain-Derived Neurotrophic Factor (BDNF))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: CHO Cells

Reinheit: > 95 % as analyzed by SDS-PAGE.

Produktdetails

Proteineigenschaft: AA 129-247

Produktmerkmale: ED50<4 μg/mL, measured in a bioassay using C6 cells.

Endotoxin-Niveau: < 0.2 EU/μg, determined by LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstituted in ddH2O or PBS at 100 μg/mL.

Buffer: Lyophilized after extensive dialysis against PBS.

Lagerung: -80 °C

Informationen zur Lagerung: Lyophilized recombinant human BDNF remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, human BDNF should be stable up to 1 week at 4°C or up to 2 months at -20°C.

Haltbarkeit: 6 months

Antigendetails

Target: BDNF (Brain-Derived Neurotrophic Factor (BDNF))

Andere Bezeichnung: BDNF

Hintergrund: BDNF, also known as brain-derived neurotrophic factor and abrineurin, is a neurotrophin belonging to the NGF-beta family. It is expressed highly in the brain, and moderately in the heart, lung, skeletal muscle and placenta. BDNF signals through its high affinity receptor gp145/trkB to exert neurotrophic properties. It has been shown to be involved in the survival and differentiation of both the central and peripheral nervous system. Specifically, BDNF regulates synaptic transmission, axonal growth and path-finding, as well as dendritic growth and morphology.
Synonyms: brain-derived neurotrophic factor, abrineurin

Molekulargewicht: 12-14 kDa, observed by reducing SDS-PAGE.

UniProt: P23560

Pathways: RTK Signalweg, Synaptic Membrane, Feeding Behaviour, Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity