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DcR1 Protein (Tumor Necrosis Factor Receptor Superfamily, Member 10c) (AA 26-221) (His tag,Fc Tag)

TNFRSF10C Spezies: Human Wirt: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN1691550
$203.50
Zzgl. Versandkosten $45.00
Lieferung in 4 Werktagen
  • Target Alle DcR1 (TNFRSF10C) Proteine anzeigen
    DcR1 (TNFRSF10C) (Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 26-221
    Spezies
    Human
    Quelle
    • 2
    • 2
    • 2
    • 1
    • 1
    Human Cells
    Aufreinigungstag / Konjugat
    Dieses DcR1 Protein ist gelabelt mit His tag,Fc Tag.
    Verwendungszweck
    Recombinant Human TRAIL R3/TNFRSF10C/CD263 (C-Fc-6His)
    Sequenz
    ATTARQEEVP QQTVAPQQQR HSFKGEECPA GSHRSEHTGA CNPCTEGVDY TNASNNEPSC FPCTVCKSDQ KHKSSCTMTR DTVCQCKEGT FRNENSPEMC RKCSRCPSGE VQVSNCTSWD DIQCVEEFGA NATVETPAAE ETMNTSPGTP APAAEETMNT SPGTPAPAAE ETMTTSPGTP APAAEETMTT SPGTPAVDDI EGRMDEPKSC DKTHTCPPCP APELLGGPSV FLFPPKPKDT LMISRTPEVT CVVVDVSHED PEVKFNWYVD GVEVHNAKTK PREEQYNSTY RVVSVLTVLH QDWLNGKEYK CKVSNKALPA PIEKTISKAK GQPREPQVYT LPPSREEMTK NQVSLTCLVK GFYPSDIAVE WESNGQPENN YKTTPPVLDS DGSFFLYSKL TVDKSRWQQG NVFSCSVMHE ALHNHYTQKS LSLSPGKHHH HHH
    Produktmerkmale
    Recombinant Human Tumor Necrosis Factor Receptor Superfamily Member 10C/TNFRSF10C is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Ala26-Ala221) of Human TNFRSF10C fused with a polyhistidine tag at the C-terminus.
    Reinheit
    > 95 % as determined by reducing SDS-PAGE.
    Sterilität
    0.2 μm filtered
    Endotoxin-Niveau
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    Handhabung
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Lagerung
    4 °C/-20 °C/-80 °C
    Informationen zur Lagerung
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Haltbarkeit
    5 months
  • Target
    DcR1 (TNFRSF10C) (Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C))
    Andere Bezeichnung
    TNFRSF10C (TNFRSF10C Produkte)
    Synonyme
    CD263, DCR1, DCR1-TNFR, LIT, TRAIL-R3, TRAILR3, TRID, TNFRSF10C, TNF receptor superfamily member 10c, TNFRSF10C
    Sub Type
    Fusionprotein
    Hintergrund
    Tumor Necrosis Factor Receptor Superfamily Member 10C (TNFRSF10C) is a glycosyl-phosphatidylinositol-linked membrane protein which binds TRAIL with high affinity. TNFRSF10C has the TRAIL-binding extracellular cysteine-rich domains, lacks the intracellular signaling domain. As a result, binding of TRAIL to TRAIL R3 doesn’t transduce an apoptosis signal. The expression of TRAIL R3 gene has been shown to protect cells bearing TRAIL R1 and/or TRAIL R2 from TRAIL-induced apoptosis.
    Alternative Names: Tumor Necrosis Factor Receptor Superfamily Member 10C, Antagonist Decoy Receptor for TRAIL/Apo-2L, Decoy TRAIL Receptor Without Death Domain, Decoy Receptor 1, DcR1, Lymphocyte Inhibitor of TRAIL, TNF-Related Apoptosis-Inducing Ligand Receptor 3, TRAIL Re
    Molekulargewicht
    48.7 kDa
    UniProt
    O14798
    Pathways
    Apoptose
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