DcR1 Protein (AA 26-221) (His tag)
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- Target Alle DcR1 (TNFRSF10C) Proteine anzeigen
- DcR1 (TNFRSF10C) (Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 26-221
- Spezies
- Human
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Quelle
- Human Cells
- Aufreinigungstag / Konjugat
- Dieses DcR1 Protein ist gelabelt mit His tag.
- Verwendungszweck
- Recombinant Human TRAIL R3/TNFRSF10C/CD263 (C-6His)
- Sequenz
- ATTARQEEVP QQTVAPQQQR HSFKGEECPA GSHRSEHTGA CNPCTEGVDY TNASNNEPSC FPCTVCKSDQ KHKSSCTMTR DTVCQCKEGT FRNENSPEMC RKCSRCPSGE VQVSNCTSWD DIQCVEEFGA NATVETPAAE ETMNTSPGTP APAAEETMNT SPGTPAPAAE ETMTTSPGTP APAAEETMTT SPGTPAVDHH HHHH
- Produktmerkmale
- Recombinant Human Tumor Necrosis Factor Receptor Superfamily Member 10C/TNFRSF10C produced by transfected human cells is a secreted protein with sequence(Ala26-Ala221) of Human TNFRSF10C fused with a polyhistidine tag at the C-terminus.
- Reinheit
- > 95 % as determined by reducing SDS-PAGE.
- Sterilität
- 0.2 μm filtered
- Endotoxin-Niveau
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product TNFRSF10C Protein
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Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C) (AA 24-236) protein (His tag)
TNFRSF10C Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C) (AA 1-259) protein (GST tag)TNFRSF10C Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C) (AA 26-236) protein (His tag)Crystallography grade TNFRSF10C Spezies: Human Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C) proteinTNFRSF10C Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
- Handhabung
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Lagerung
- 4 °C/-20 °C/-80 °C
- Informationen zur Lagerung
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. - Haltbarkeit
- 3 months
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- Target
- DcR1 (TNFRSF10C) (Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C))
- Andere Bezeichnung
- trail-r3 (TNFRSF10C Produkte)
- Synonyme
- CD263 Protein, DCR1 Protein, DCR1-TNFR Protein, LIT Protein, TRAIL-R3 Protein, TRAILR3 Protein, TRID Protein, TNFRSF10C Protein, TNF receptor superfamily member 10c Protein, TNFRSF10C Protein
- Sub Type
- Fusionprotein
- Hintergrund
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Tumor Necrosis Factor Receptor Superfamily Member 10C (TNFRSF10C) is a glycosyl-phosphatidylinositol-linked membrane protein which binds TRAIL with high affinity. TNFRSF10C has the TRAIL-binding extracellular cysteine-rich domains, lacks the intracellular signaling domain. As a result, binding of TRAIL to TRAIL R3 doesn’t transduce an apoptosis signal. The expression of TRAIL R3 gene has been shown to protect cells bearing TRAIL R1 and/or TRAIL R2 from TRAIL-induced apoptosis.
Alternative Names: Tumor Necrosis Factor Receptor Superfamily Member 10C, Antagonist Decoy Receptor for TRAIL/Apo-2L, Decoy TRAIL Receptor Without Death Domain, Decoy Receptor 1, DcR1, Lymphocyte Inhibitor of TRAIL, TNF-Related Apoptosis-Inducing Ligand Receptor 3, TRAIL Re - Molekulargewicht
- 21.78 kDa
- UniProt
- O14798
- Pathways
- Apoptose
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