(serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 (SERPINF1))
The protein encoded by this gene is a member of the serpin family, although it does not display the serine protease inhibitory activity shown by many of the other serpin family members. The encoded protein is secreted and strongly inhibits angiogenesis. In addition, this protein is a neurotrophic factor involved in neuronal differentiation in retinoblastoma cells.[provided by RefSeq, Mar 2011].
Deng, Gui, Kim, Xie, Chen, Li, He, Chen, Chen, Luo, Lu, Xie, Churchill, Xu, Zhou, Wu, Yu, John, Hirayasu, Nguyen, Liu, Huang, Li, Deng, Tang, Sadek, Zhang, Huang, Zou, Chen, Zhu, Arase, Xia, Jiang et al.: "LILRB4 signalling in leukaemia cells mediates T cell suppression and tumour infiltration. ..." in: Nature, Vol. 562, Issue 7728, pp. 605-609, (2019) (PubMed).
Zhang, Dai, Neng, Zhang, Zhi, Fridberger, Shi: "Perivascular macrophage-like melanocyte responsiveness to acoustic trauma--a salient feature of strial barrier associated hearing loss." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 27, Issue 9, pp. 3730-40, (2013) (PubMed).
Aliase für PEDF Proteine
serpin family F member 1 (SERPINF1) Proteine serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 (serpinf1) Proteine serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 L homeolog (serpinf1.L) Proteine serpin family F member 1 (Serpinf1) Proteine serine (or cysteine) peptidase inhibitor, clade F, member 1 (Serpinf1) Proteine AI195227 Proteine Dmrs91 Proteine EPC-1 Proteine MGC82984 Proteine OI6 Proteine OI12 Proteine PEDF Proteine Pedf Proteine Pedfl Proteine Sdf3 Proteine SERPINF1 Proteine zgc:92072 Proteine