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anti-RGS14 (RGS14) Antikörper

Bezeichnung:: anti-Regulator of G-Protein Signaling 14 Antikörper (RGS14)

Auf www.antikoerper-online.de finden Sie aktuell 106 Regulator of G-Protein Signaling 14 (RGS14) Antikörper von 24 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen RGS14 Proteine (8) und und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 121 RGS14 Produkte verfügbar.

Synonyme:: MGC80558, rgs14, RPIP1, wu:fi04g12

Alle Antikörper anzeigen	Gen	GeneID	UniProt
	RGS14	10636	O43566
	RGS14	51791	P97492
	RGS14	114705	O08773
Alle Spezies anzeigen Weitere Synonyme anzeigen

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anti-Mouse (Murine) RGS14 Antikörper:

anti-Rat (Rattus) RGS14 Antikörper:

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Verknüpfte Pathways mit anti-RGS14 Antikörper

Platelet-derived growth Factor Receptor Signaling

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Am meisten referenzierte anti-RGS14 Antikörper

Mammalian Monoclonal RGS14 Primary Antibody für ISt, IHC - ABIN1304933 : Llorens-Martín, Jurado-Arjona, Avila, Hernández: Novel connection between newborn granule neurons and the hippocampal CA2 field. in Experimental neurology 2014 (PubMed)
Show all 8 Pubmed References
Human Polyclonal RGS14 Primary Antibody für ELISA, WB - ABIN250233 : Snow, Antonio, Suggs, Gutstein, Siderovski: Molecular cloning and expression analysis of rat Rgs12 and Rgs14. in Biochemical and biophysical research communications 1997 (PubMed)

Weitere Antikörper gegen RGS14 Interaktionspartner

Human Regulator of G-Protein Signaling 14 (RGS14) Interaktionspartner

The findings of this study suggested new pre- and postsynaptic regulatory functions of RGS14 and RGS14 variants, specific to the primate brain, and provide evidence for unconventional roles of RGS14 in the nuclei of striatal neuron.
Data support the notion that the Galpha, but not Gbetagamma, arm of the Gi/o signalling is involved in TRPC4 activation and unveil new roles for RGS and RGS14 in fine-tuning TRPC4 activities.
The RBD region associates with the RGS domain region, producing an intramolecular interaction within RGS14 that enhances the GTPase activating function.
RGS14 can form complexes with GPCRs in cells that are dependent on Galpha(i/o) and these RGS14.Galpha(i1).GPCR complexes may be substrates for other signaling partners such as Ric-8A
RGS-14 may facilitate cognitive processing by modulating Cav1 channel-mediated intracellular divalent calcium ion Ca(2)+ transients.
RGS14 serves as a novel scaffold to integrate GTP-Binding Protein alpha Subunit and Ras/Raf/MAPkinase signalling events through the action of its GL domain.
We show that RGS14 is a component of mitotic asters formed in vitro from HeLa cell extracts and that depletion of RGS14 from cell extracts blocks aster formation.
NMR 1H, 13C and 15N resonances of the RGS domain (residues 56-207)

Mouse (Murine) Regulator of G-Protein Signaling 14 (RGS14) Interaktionspartner

demonstrate that RGS14 is a novel CaM effector and CaMKII phosphorylation substrate thereby providing new insight into mechanisms by which RGS14 controls plasticity in CA2 neurons.
The studies results demonstrate for the first time that RGS14 regulates plasticity in hippocampal area CA2 by restricting Ca(2+) elevations in CA2 spines and downstream signaling pathways.
Study shows that RGS14 mRNA and protein are upregulated throughout postnatal mouse development, and RGS14 protein exhibits a dynamic localization pattern that is enriched in hippocampus and primary olfactory cortex in the adult mouse brain
Inactive Galpha(i1)-GDP enhances the affinity of RGS14 for H-Ras-GTP in live cells, resulting in a ternary signaling complex that is further regulated by G protein-coupled receptors.
Activation of the Rsg14-Galphai1-GDP signaling complex is regulated by Ric8.
These results demonstrate that RGS14 is a key regulator of signaling pathways linking synaptic plasticity in CA2 pyramidal neurons to hippocampal-based learning and memory but distinct from the canonical DG-CA3-CA1 circuit.
the RGS14 GoLoco domain discriminates among Galphai isoforms
RGS14 is found ubiquitously throughout the postimplantation period in mice
RGS14 activity towards heterotrimeric G-proteins, as either a GAP or a guanine nucleotide dissociation inhibitor, was unaffected by Rap binding.
Morphine activation of Mu opioid receptors RGS14 prevents G-protein-coupled receptor kinases from phosphorylating those residues required for receptor endocytosis.

Zebrafish Regulator of G-Protein Signaling 14 (RGS14) Interaktionspartner

The regulator of G-protein signaling 14a protein, regulates the temporal relations between the appearance of the guidance molecules and the acquisition of cellular motility by regulating E-cadherin levels.

RGS14 Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

Alternative names and synonyms associated with RGS14

regulator of G protein signaling 14 (RGS14) Antikörper
regulator of G-protein signaling 14 (Rgs14) Antikörper
regulator of G-protein signaling 14 L homeolog (rgs14.L) Antikörper
regulator of G-protein signaling 14 (RGS14) Antikörper
regulator of G-protein signalling 14 (rgs14) Antikörper
regulator of G protein signaling 14 (Rgs14) Antikörper
regulator of G protein signaling 14a (rgs14a) Antikörper

MGC80558 Antikörper
rgs14 Antikörper
RPIP1 Antikörper
wu:fi04g12 Antikörper

Bezeichner auf Proteinebene für RGS14

regulator of G-protein signalling 14 , RAP1/RAP2-interacting protein , rap1/rap2 interacting protein , regulator of G-protein signaling 14 , Regulator of G-protein signaling 14 , regulator of G-protein signaling 14-like , LOW QUALITY PROTEIN: regulator of G-protein signaling 14

GENE ID	SPEZIES
10636	Homo sapiens
51791	Mus musculus
114705	Rattus norvegicus
444133	Xenopus laevis
471758	Pan troglodytes
489092	Canis lupus familiaris
532605	Bos taurus
699625	Macaca mulatta
769193	Gallus gallus
100195412	Salmo salar
100404112	Callithrix jacchus
100476010	Ailuropoda melanoleuca
100524790	Sus scrofa
100585478	Nomascus leucogenys
100728156	Cavia porcellus
327368	Danio rerio
101106525	Ovis aries musimon

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