MLH1 Produkte
(MutL Homolog 1 (MLH1))
Kategorien
This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.[provided by RefSeq, Nov 2009].
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Ausgewählte MLH1 Kategorien
MLH1 Antikörper
High quality antibodies with extensive validation data.
MLH1 ELISA Kits
Reliable ELISA kits for a wide range of species.
MLH1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene MLH1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, FACS, ICC
Validierungen
- (6)
Kat. Nr.
ABIN7193525
Menge
0.1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, FACS
Validierungen
- (7)
Kat. Nr.
ABIN7193587
Menge
0.1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF, IHC (p), PLA
Validierungen
- (7)
Kat. Nr.
ABIN561826
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene MLH1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6957921
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene MLH1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7124036
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1311006
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1311004
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren MLH1 Produkten
: "Integrated Proteomic and Transcriptomic Analysis Reveals Long Noncoding RNA HOX Transcript Antisense Intergenic RNA (HOTAIR) Promotes Hepatocellular Carcinoma Cell Proliferation by Regulating Opioid ..." in: Molecular & cellular proteomics : MCP, Vol. 17, Issue 1, pp. 146-159, (2019) (PubMed).: "miRNA-148b regulates radioresistance in non-small lung cancer cells via regulation of MutL homologue 1." in: Bioscience reports, Vol. 36, Issue 3, (2016) (PubMed).
: "Modulation of mismatch repair and genomic stability by miR-155. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 15, pp. 6982-7, (2010) (PubMed).
: "Nuclear overexpression of mitotic regulatory proteins in biliary tract cancer: correlation with clinicopathologic features and patient survival." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 18, Issue 2, pp. 417-23, (2009) (PubMed).
: "High-dose rapid and standard induction chemotherapy for patients aged over 1 year with stage 4 neuroblastoma: a randomised trial." in: The lancet oncology, Vol. 9, Issue 3, pp. 247-56, (2008) (PubMed).
: "Gene-related cancer spectrum in families with hereditary non-polyposis colorectal cancer (HNPCC)." in: Familial cancer, Vol. 7, Issue 2, pp. 163-72, (2008) (PubMed).
: "CXCR6 is expressed on T cells in both T helper type 1 (Th1) inflammation and allergen-induced Th2 lung inflammation but is only a weak mediator of chemotaxis." in: Immunology, Vol. 121, Issue 4, pp. 555-64, (2007) (PubMed).
: "A novel role for DNA mismatch repair and the autophagic processing of chemotherapy drugs in human tumor cells." in: Autophagy, Vol. 3, Issue 4, pp. 368-70, (2007) (PubMed).
: "Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing over." in: Nature genetics, Vol. 13, Issue 3, pp. 336-42, (1996) (PubMed).
: "Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer of human MutL homologs." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, Issue 6, pp. 1950-4, (1995) (PubMed).
Synonyme und alternative Namen zu MLH1
mutL homolog 1 (MLH1), CG11482 gene product from transcript CG11482-RB (Mlh1), mutL homolog 1 S homeolog (mlh1.S), mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) (mlh1), DNA mismatch repair protein Mlh1 (LOC588545), mutL homolog 1 (mlh1), mutL homolog 1 (Mlh1), 1110035C23Rik, AI317206, AI325952, AI561766, CG11482, COCA2, Dmel\\CG11482, dmlh-1, dmlh1, FCC2, hMLH1, HNPCC, HNPCC2, LOC100232198, MLH1, zgc:66301Bezeichner auf Proteinebene für MLH1
- MutL protein homolog 1
- CG11482-PA
- CG11482-PB
- Mlh1-PA
- Mlh1-PB
- DNA mismatch repair protein Mlh1
- mutL-like protein 1
- mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
- DNA mismatch repair protein Mlh1-like
- colon cancer, nonpolyposis type 2
- mutL protein homolog 1
- mismatch repair protein 1
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