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MLL2 Produkte

(Myeloid/lymphoid Or Mixed-Lineage Leukemia 2 (MLL2))

Kategorien

This gene encodes a protein which contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY-rich domains, and a SET (suppressor of variegation, enhancer of zeste, and trithorax) domain. The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL (mixed-lineage leukemia) family. This gene is ubiquitously expressed in adult tissues. It is also amplified in solid tumor cell lines, and may be involved in human cancer. Two alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene, however, the full length nature of the shorter transcript is not known. [provided by RefSeq, Jul 2008].

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Ausgewählte MLL2 Kategorien

MLL2 Antikörper

High quality antibodies with extensive validation data.

MLL2 ELISA Kits

Reliable ELISA kits for a wide range of species.

Empfohlene MLL2 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC (p)
Validierungen
  • (3)
  • (3)
Kat. Nr. ABIN6243263
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, WB
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN948660
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, IHC (p), IHC
Validierungen
  • (2)
Kat. Nr. ABIN1494780
Menge 50 μg
Datenblatt Datenblatt

Empfohlene MLL2 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Monkey
Analytical Method Quantitative Competition ELISA
Validierungen
Kat. Nr. ABIN1503552
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Dog
Analytical Method Quantitative Competition ELISA
Validierungen
Kat. Nr. ABIN1503551
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Goat
Analytical Method
Validierungen
Kat. Nr. ABIN1503549
Menge 96 tests
Datenblatt Datenblatt

Empfohlene MLL2 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1311012
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren MLL2 Produkten

Micale, Augello, Maffeo, Selicorni, Zucchetti, Fusco, De Nittis, Pellico, Mandriani, Fischetto, Boccone, Silengo, Biamino, Perria, Sotgiu, Serra, Lapi, Neri, Ferlini, Cavaliere, Chiurazzi, Monica et al.: "Molecular analysis, pathogenic mechanisms, and readthrough therapy on a large cohort of Kabuki syndrome patients. ..." in: Human mutation, Vol. 35, Issue 7, pp. 841-50, (2014) (PubMed).

Kim, Sharma, Dhar, Lee, Gu, Chan, Lin, Lee: "UTX and MLL4 coordinately regulate transcriptional programs for cell proliferation and invasiveness in breast cancer cells." in: Cancer research, Vol. 74, Issue 6, pp. 1705-17, (2014) (PubMed).

Bhan, Hussain, Ansari, Bobzean, Perrotti, Mandal: "Bisphenol-A and diethylstilbestrol exposure induces the expression of breast cancer associated long noncoding RNA HOTAIR in vitro and in vivo." in: The Journal of steroid biochemistry and molecular biology, Vol. 141, pp. 160-70, (2014) (PubMed).

Dhar, Lee, Kan, Voigt, Ma, Shi, Reinberg, Lee: "Trans-tail regulation of MLL4-catalyzed H3K4 methylation by H4R3 symmetric dimethylation is mediated by a tandem PHD of MLL4." in: Genes & development, Vol. 26, Issue 24, pp. 2749-62, (2012) (PubMed).

Synonyme und alternative Namen zu MLL2

lysine methyltransferase 2D (KMT2D), lysine methyltransferase 2B (KMT2B), lysine (K)-specific methyltransferase 2D (Kmt2d), myeloid/lymphoid or mixed-lineage leukemia 2 (MLL2), lysine methyltransferase 2D (Kmt2d), AAD10, ALR, BC032281, BC058659, C430014K11Rik, CAGL114, HRX2, KABUK1, KMS, KMT2B, MLL1B, MLL2, Mll2, MLL4, Mll4, TNRC21, TRX2, WBP7

Bezeichner auf Proteinebene für MLL2

  • ALL1-related protein
  • Kabuki make-up syndrome
  • Kabuki mental retardation syndrome
  • histone-lysine N-methyltransferase 2D
  • histone-lysine N-methyltransferase MLL2
  • lysine N-methyltransferase 2D
  • myeloid/lymphoid or mixed-lineage leukemia 2
  • trinucleotide repeat containing 21
  • KMT2D
  • WBP-7
  • WW domain binding protein 7
  • WW domain-binding protein 7
  • histone-lysine N-methyltransferase 2B
  • histone-lysine N-methyltransferase MLL4
  • lysine N-methyltransferase 2B
  • mixed lineage leukemia gene homolog 2
  • myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) 4
  • myeloid/lymphoid or mixed-lineage leukemia 4
  • myeloid/lymphoid or mixed-lineage leukemia protein 4
  • trithorax homolog 2
  • trithorax homologue 2
  • myeloid/lymphoid or mixed-lineage leukemia protein 2
  • LOW QUALITY PROTEIN: histone-lysine N-methyltransferase 2D
  • lysine (K)-specific methyltransferase 2D
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