anti-Complement Factor H (CFH) Antikörper

Bezeichnung:
anti-Complement Factor H Antikörper (CFH)
Auf www.antikoerper-online.de finden Sie aktuell 264 Complement Factor H (CFH) Antikörper von 25 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Complement Factor H Kits (56) und Complement Factor H Proteine (18) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 347 Complement Factor H Produkte verfügbar.
Synonyme:
AHUS1, AMBP1, ARMD4, ARMS1, CFH, CFHL3, fH, FHL1, HF, HF1, HF2, HUS, im:7147412, Mud-1, NOM, Sas-1, Sas1, si:ch211-207o17.2
Alle Antikörper anzeigen Gen GeneID UniProt
CFH 12628 P06909
CFH 3075 P08603
CFH 155012  

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Meistgesuchte Reaktivitäten zu anti-Complement Factor H (CFH) Antikörper

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anti-Mouse (Murine) Complement Factor H Antikörper:

anti-Human Complement Factor H Antikörper:

anti-Rat (Rattus) Complement Factor H Antikörper:

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Am meisten referenzierte anti-Complement Factor H Antikörper

  1. Human Monoclonal Complement Factor H Primary Antibody für FACS - ABIN2660858 : Ripoche, Day, Harris, Sim: The complete amino acid sequence of human complement factor H. in The Biochemical journal 1988 (PubMed)
    Zeige alle 6 Referenzen für 2660858

  2. Human Polyclonal Complement Factor H Primary Antibody für EIA, IF - ABIN951646 : Dieterich, Hammerschmidt, Richter, Skerka, Wallich, Matuschka, Zipfel, Kraiczy: Inadequate binding of immune regulator factor H is associated with sensitivity of Borrelia lusitaniae to human complement. in Infection and immunity 2010 (PubMed)
    Zeige alle 3 Referenzen für 951646

  3. Human Polyclonal Complement Factor H Primary Antibody für IF, IHC (p) - ABIN654896 : Scambi, La Verde, De Franceschi, Barausse, Poli, Benedetti, Sorio, Deriu, Roncada, Bortolami, Turrini, Caramaschi, Stranieri, Bambara, Biasi: Comparative proteomic analysis of serum from patients with systemic sclerosis and sclerodermatous GVHD. Evidence of defective function of factor H. in PLoS ONE 2010 (PubMed)
    Zeige alle 2 Referenzen für 654896

  4. Human Monoclonal Complement Factor H Primary Antibody für EIA, FACS - ABIN181114 : Alexander, Quigg: The simple design of complement factor H: Looks can be deceiving. in Molecular immunology 2006 (PubMed)
    Zeige alle 2 Referenzen für 181114

  5. Horse (Equine) Polyclonal Complement Factor H Primary Antibody für EIA, ID - ABIN113017 : Chung, Liszewski, Nybakken, Davis, Townsend, Fremont, Atkinson, Diamond: West Nile virus nonstructural protein NS1 inhibits complement activation by binding the regulatory protein factor H. in Proceedings of the National Academy of Sciences of the United States of America 2006 (PubMed)

  6. Human Polyclonal Complement Factor H Primary Antibody für ELISA, WB - ABIN250548 : Klein, Zeiss, Chew, Tsai, Sackler, Haynes, Henning, SanGiovanni, Mane, Mayne, Bracken, Ferris, Ott, Barnstable, Hoh: Complement factor H polymorphism in age-related macular degeneration. in Science (New York, N.Y.) 2005 (PubMed)

Weitere Antikörper gegen Complement Factor H Interaktionspartner

Chimpanzee Complement Factor H (CFH) Interaktionspartner

  1. interaction between sialylated Neisseria gonorrhoeae and factor H [factor H]

Zebrafish Complement Factor H (CFH) Interaktionspartner

  1. Results report the molecular cloning and identification of complement factor H and complement factor H-like 1-4 (CFHL1 (zeige CFHR1 Antikörper)-4) in Danio rerio.

Mouse (Murine) Complement Factor H (CFH) Interaktionspartner

  1. VEGF (zeige VEGFA Antikörper) inhibition decreases local CFH and other complement regulators in the eye and kidney through reduced VEGFR2 (zeige KDR Antikörper)/PKC-alpha (zeige PKCa Antikörper)/CREB (zeige CREB1 Antikörper) signaling.

  2. environmental factors can drive retinal disease in these mice when linked to complement deficits impairing immune function. Both groups of mice had similar levels of retinal amyloid beta accumulation. Consequently there is no direct link between this and inflammation in Cfh(-/-) mice.

  3. absence of plasma CfH conferred susceptibility to glomerulonephritis

  4. This new understanding of the complicated interactions of CFH in AMD (zeige AMD1 Antikörper)-like pathology provides an improved foundation for the development of targeted therapies for AMD (zeige AMD1 Antikörper)

  5. data suggest that altered interactions of Cfh with MDA-modified proteins may be relevant in explaining the effects of the Cfh variant.

  6. Cfh and Cfhr2 (zeige CFHR2 Antikörper) genes are expressed in the mouse outer retina. Only Cfh mRNA was detected in the retinal pigment epithelium, but no protein.

  7. A spectrum of complement dysregulation was modeled on the APOE4 age related macular degeneration mouse model by crossing these mice to complement factor H knockout (cfh-/-) mice to test the impact of excess complement activation.

  8. Data indicate that co-deficiency of factor H (FH) and MASP-1/MASP-3 (zeige MASP1 Antikörper) did not ameliorate either the plasma Complement C3 (zeige C3 Antikörper) (C3) activation or glomerular C3 accumulation in FH-deficient mice.

  9. A2E accumulation altered retinal microglial complement regulation by decreasing complement factor H (and increasing complement factor B (zeige CFB Antikörper) expression), favoring increased complement activation and lipofuscin deposition in the outer retina.

  10. The exaggerated humoral immune response in CFH(-/-) mice was normalized in CFH(-/-)C5aR (zeige C5AR1 Antikörper)(-/-) double knockout mice, highlighting the C5aR (zeige C5AR1 Antikörper) dependence.

Human Complement Factor H (CFH) Interaktionspartner

  1. VEGF (zeige VEGFA Antikörper) inhibition decreases local CFH and other complement regulators in the eye and kidney through reduced VEGFR2 (zeige KDR Antikörper)/PKC-alpha (zeige PKCa Antikörper)/CREB (zeige CREB1 Antikörper) signaling.

  2. CFH rs1061170 has an important effect on age at onset of MDD in Han Chinese and may therefore be related to early pathogenesis of MDD.

  3. Data suggest that disease-linked mutations in complement factor H (CFH) affect pivotal role of CFH in regulation of complement activation; mutations studied include those linked to atypical hemolytic uremic syndrome and age-related macular degeneration.

  4. Fibrinogen gamma chain (zeige FGG Antikörper) and complement factor H were found to be bound as a protein complex in the plasma of a patient with advanced ovarian cancer

  5. Factor I binds C3b-Factor H between Factor H domains 2 and 3 and a reoriented C3b C-terminal domain and docks onto the first scissile bond, while stabilizing its catalytic domain for proteolytic activity.

  6. The VEGF (zeige VEGFA Antikörper) haplotype TGA (zeige TBX1 Antikörper) could be used as a marker for poor visual prognosis in Tunisian patients with neovascular AMD (zeige AMD1 Antikörper) treated with bevacizumab.

  7. Two protective, low-frequency, non-synonymous variants were significantly associated with a decrease in age-related macular degeneration (AMD (zeige AMD1 Antikörper))risk: A307V in PELI3 (zeige PELI3 Antikörper) and N1050Y in CFH .We also identified a strong protective signal for a common variant (rs8056814) near CTRB1 (zeige CTRB1 Antikörper) associated with a decrease in AMD (zeige AMD1 Antikörper) risk (logistic regression: OR = 0.71, P = 1.8 x 10-07).

  8. this study shows that RNA interference of factor H in dendritic cells increased alloantigen-specific T-cell proliferation

  9. monomeric CRP (zeige CRP Antikörper) (mCRP) but not the pentameric form (pCRP) upregulates IL-8 (zeige IL8 Antikörper) and CCL2 (zeige CCL2 Antikörper) levels in retinal pigment epithelial cells. Complement factor H (FH) binds mCRP to dampen its proinflammatory activity. FH from AMD (zeige AMD1 Antikörper) patients carrying the "risk" His402 polymorphism displays impaired binding to mCRP.

  10. The uromodulin (zeige UMOD Antikörper)-CFH interaction enhanced the cofactor activity of CFH for factor I-mediated cleavage of C3b to inactivated C3b.

Pig (Porcine) Complement Factor H (CFH) Interaktionspartner

Complement Factor H (CFH) Antigen-Profil

Beschreibung des Gens

This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Alternative names and synonyms associated with Complement Factor H (CFH)

  • complement factor H (CFH) Antikörper
  • complement factor H (cfh) Antikörper
  • complement component factor h (Cfh) Antikörper
  • complement factor H (Cfh) Antikörper
  • AHUS1 Antikörper
  • AMBP1 Antikörper
  • ARMD4 Antikörper
  • ARMS1 Antikörper
  • CFH Antikörper
  • CFHL3 Antikörper
  • fH Antikörper
  • FHL1 Antikörper
  • HF Antikörper
  • HF1 Antikörper
  • HF2 Antikörper
  • HUS Antikörper
  • im:7147412 Antikörper
  • Mud-1 Antikörper
  • NOM Antikörper
  • Sas-1 Antikörper
  • Sas1 Antikörper
  • si:ch211-207o17.2 Antikörper

Bezeichner auf Proteinebene für CFH

complement factor H , complement factor H related protein 3A4/5G4 , protein beta-1-H , H factor 1 (complement) , H factor 2 (complement) , adrenomedullin binding protein , age-related maculopathy susceptibility 1 , beta-1-H-globulin , beta-1H , factor H , factor H-like 1 , complement component factor H , complement inhibitory factor H , platelet complement factor H , complement regulator factor H

GENE ID SPEZIES
457601 Pan troglodytes
553060 Danio rerio
553297 Danio rerio
100399888 Callithrix jacchus
100451270 Pongo abelii
100465619 Ailuropoda melanoleuca
100600041 Nomascus leucogenys
12628 Mus musculus
3075 Homo sapiens
100051358 Equus caballus
155012 Rattus norvegicus
478952 Canis lupus familiaris
100733902 Cavia porcellus
100340175 Oryctolagus cuniculus
397525 Sus scrofa
280816 Bos taurus
429057 Gallus gallus
100174982 Ovis aries
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