Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
Alle Spezies anzeigen
Weitere Synonyme anzeigen
Wählen Sie die Spezies und Applikation aus
anti-Mouse (Murine) DIO3 Antikörper:
anti-Rat (Rattus) DIO3 Antikörper:
anti-Human DIO3 Antikörper:
Sie gelangen zu unserer vorgefilterten Suche.
Hamster Polyclonal DIO3 Primary Antibody für FACS, IHC (p) - ABIN446380
Kalló, Mohácsik, Vida, Zeöld, Bardóczi, Zavacki, Farkas, Kádár, Hrabovszky, Arrojo E Drigo, Dong, Barna, Palkovits, Borsay, Herczeg, Lechan, Bianco, Liposits, Fekete, Gereben: A novel pathway regulates thyroid hormone availability in rat and human hypothalamic neurosecretory neurons. in PLoS ONE 2012
Show all 9 Pubmed References
Hamster Polyclonal DIO3 Primary Antibody für ICC, IF - ABIN410067
Freitas, Gereben, Castillo, Kalló, Zeöld, Egri, Liposits, Zavacki, Maciel, Jo, Singru, Sanchez, Lechan, Bianco: Paracrine signaling by glial cell-derived triiodothyronine activates neuronal gene expression in the rodent brain and human cells. in The Journal of clinical investigation 2010
Show all 6 Pubmed References
Hamster Polyclonal DIO3 Primary Antibody für IHC (p), WB - ABIN446381
Jo, Kalló, Bardóczi, Arrojo e Drigo, Zeöld, Liposits, Oliva, Lemmon, Bixby, Gereben, Bianco: Neuronal hypoxia induces Hsp40-mediated nuclear import of type 3 deiodinase as an adaptive mechanism to reduce cellular metabolism. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2012
Show all 4 Pubmed References
Polyclonal DIO3 Primary Antibody für WB - ABIN540383
Baqui, Botero, Gereben, Curcio, Harney, Salvatore, Sorimachi, Larsen, Bianco: Human type 3 iodothyronine selenodeiodinase is located in the plasma membrane and undergoes rapid internalization to endosomes. in The Journal of biological chemistry 2003
Show all 3 Pubmed References
Polyclonal DIO3 Primary Antibody für WB - ABIN540382
Huang, Fish, Dorfman, Salvatore, Kozakewich, Mandel, Larsen: A 21-year-old woman with consumptive hypothyroidism due to a vascular tumor expressing type 3 iodothyronine deiodinase. in The Journal of clinical endocrinology and metabolism 2002
Show all 3 Pubmed References
No changes in TRb or DI-2 and DI-3 expression in tail tissue collected from Triclosan exposure larvae were found.
The expression of DIO3 on mRNA/protein levels in the depressive disorders patients was increased in comparison to the control subjects.
The expression of piRNAs encoded at DLK1-DIO3 enhances the prognostic potential of small non-coding RNAs specific to this locus in predicting lung cancer patient outcome.
A critical role for reduced intracellular TH concentrations in neutrophil function during infection, for which the TH inactivating enzyme D3 appears essential.
In neonatal skin, DIO3 exhibited a high degree of monoallelic expression from the paternal allele.
Presence and subcellular location of D3 in human neutrophils for the first time and propose a model, in which D3 plays a role in the bacterial killing capacity of neutrophils either through generation of iodide for the myeloperoxidase system or through modulation of intracellular Thyroid hormone bioavailability.
MAPK and SHH pathways modulate type 3 deiodinase expression in papillary thyroid carcinoma
D3 is a critical factor in testis development and in testicular protection from thyrotoxicosis.
Thyroid hormone deiodinases D1, D2, and D3 are differentially expressed in endothelial cells following thyroid hormone exposure.
the microRNA cluster at the Dlk1-Dio3 locus is upregulated in lung adenocarcinoma
[review] D3 polymorphisms show no relationship with inter-individual variation in serum thyroid hormone parameters.
Overall, the data suggest that active expression of the DLK1-DIO3 cluster represents a new biomarker for epigenetic stability of hESCs and indicates the importance of using a proper physiological oxygen level during the derivation and culture of hESCs.
the imprinted DLK1-DIO3 locus is regulated by noncoding RNA IPW in an induced pluripotent stem cell model of Prader-Willi syndrome
Data indicate that Na+/I- symporter and type 3 iodothyronine deiodinase genes are expressed in term placenta and amniotic membrane.
Treatment with high affinity amyloidbeta42 oligomer-binding enantiomeric D3 peptide significantly decreases amyloidbeta deposits and the associated inflammatory response and improves cognition, even when applied only at late stages and high age.
D3 expression is re-activated in various types of human cancers. It may play a role in carcinogenesis and neoplastic cell proliferation. Review.
Reviewed are the microRNAs within the DLK1-DIO3 genomic region, their role in controlling tissue homeostasis and in the pathogenesis of some human diseases, mostly cancer, when aberrantly expressed. [review]
Deiodinase iodothyronine type III activity was increased in all papillary thyroid carcinomas as compared with that in adjacent thyroid tissue, parallel with ~ 5 times increase in deiodinase iodothyronine type III mRNA levels.
D3 expression in perinatal pancreatic beta-cells prevents untimely exposure to thyroid hormone, the absence of which leads to impaired beta-cell function and subsequently insulin secretion and glucose homeostasis
coordinate up-regulation of the DLK1-DIO3 miRNA cluster at 14q32.2 may define a novel molecular (stem cell-like) subtype of hepatocellular carcinoma associated with poor prognosis
[review] progress made in understanding the physiological function and significance of D3; summarizes the intriguing evidence that D3 plays a pivotal role in defining local TH concentration in the developing fetus and in several conditions in adult life.
The imprinted gene DIO3 is a candidate gene for litter size in pigs
DIO3 gene polymorphism was significantly associated with almost all fat deposition and carcass traits.
expression of D3 was observed in cerebrum and was positively regulated by thyroid state.
An allele-specific expression analysis-based SNP method revealed that DIO3 and DIO3OS genes exhibited monoallelic expression in the eight tissues, indicating that DIO3 and DIO3OS are imprinted in cattle.
The protein encoded by this intronless gene belongs to the iodothyronine deiodinase family. It catalyzes the inactivation of thyroid hormone by inner ring deiodination of the prohormone thyroxine (T4) and the bioactive hormone 3,3',5-triiodothyronine (T3) to inactive metabolites, 3,3',5'-triiodothyronine (RT3) and 3,3'-diiodothyronine (T2), respectively. This enzyme is highly expressed in the pregnant uterus, placenta, fetal and neonatal tissues, suggesting that it plays an essential role in the regulation of thyroid hormone inactivation during embryological development. This protein contains a selenocysteine (Sec) residue, which is essential for efficient enzyme activity. The selenocysteine is encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal.
type III iodothyronine deiodinase
, Type 3 DI
, Type-III 5'-deiodinase
, type 3 iodothyronine deiodinase
, deiodinase, iodothyronine, type III
, gene 15
, type 3 deiodinase
, iodothyronine 5-deiodinase type III
, type 3 DI
, type-III 5'-deiodinase
, deiodinase, iodothyronine, type 3
, iodothyronine deiodinase, placental type
, thyroxine deiodinase type III (selenoprotein)
, type 3 iodothyronine selenodeiodinase
, type-III 5' deiodinase
, iodothyronine deiodinase type III