GCK Produkte
(Glucokinase (Hexokinase 4) (GCK))
Kategorien
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), maturity onset diabetes of the young, type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI). [provided by RefSeq, Apr 2009].
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Ausgewählte GCK Kategorien
GCK Antikörper
High quality antibodies with extensive validation data.
GCK ELISA Kits
Reliable ELISA kits for a wide range of species.
GCK Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene GCK Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IF
Validierungen
- (6)
Kat. Nr.
ABIN515989
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
- (2)
- (3)
Kat. Nr.
ABIN969172
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Mouse
Applikation
WB, IHC, IP, ICC
Validierungen
- (3)
Kat. Nr.
ABIN7429088
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene GCK ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6956118
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6967028
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6963157
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene GCK Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1354918
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1354920
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7123102
Menge
50 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren GCK Produkten
: "Hypoglycemic effects of wheat bran alkyresorcinols in high-fat/high-sucrose diet and low-dose streptozotocin-induced type 2 diabetic male mice and protection of pancreatic β cells." in: Food & function, Vol. 10, Issue 6, pp. 3282-3290, (2019) (PubMed).: "Paeonol Ameliorates Glucose and Lipid Metabolism in Experimental Diabetes by Activating Akt." in: Frontiers in pharmacology, Vol. 10, pp. 261, (2019) (PubMed).
: "Improvement of Lipid and Glucose Metabolism by Capsiate in Palmitic Acid-Treated HepG2 Cells via Activation of the AMPK/SIRT1 Signaling Pathway." in: Journal of agricultural and food chemistry, Vol. 66, Issue 26, pp. 6772-6781, (2018) (PubMed).
: "Vitamin C and E chronic supplementation differentially affect hepatic insulin signaling in rats." in: Life sciences, Vol. 194, pp. 196-204, (2018) (PubMed).
: "Effects of a Novel Glucokinase Activator, HMS5552, on Glucose Metabolism in a Rat Model of Type 2 Diabetes Mellitus." in: Journal of diabetes research, Vol. 2017, pp. 5812607, (2017) (PubMed).
: "Anti-diabetes effect of chronic intermittent hypobaric hypoxia through improving liver insulin resistance in diabetic rats." in: Life sciences, Vol. 150, pp. 1-7, (2016) (PubMed).
: "MicroRNA-130a can inhibit hepatitis B virus replication via targeting PGC1α and PPARγ." in: RNA (New York, N.Y.), Vol. 21, Issue 3, pp. 385-400, (2015) (PubMed).
: "The Possible Mechanisms of the Impaired Insulin Secretion in Hypothyroid Rats." in: PLoS ONE, Vol. 10, Issue 7, pp. e0131198, (2015) (PubMed).
: "Role of glucokinase in the subcellular localization of glucokinase regulatory protein." in: International journal of molecular sciences, Vol. 16, Issue 4, pp. 7377-93, (2015) (PubMed).
: "Opposite clinical phenotypes of glucokinase disease: Description of a novel activating mutation and contiguous inactivating mutations in human glucokinase (GCK) gene." in: Molecular endocrinology (Baltimore, Md.), Vol. 23, Issue 12, pp. 1983-9, (2009) (PubMed).
Synonyme und alternative Namen zu GCK
glucokinase (GCK), glucokinase (Gck), glucokinase (glcK), glucokinase (Bphyt_1025), glucokinase (Halhy_6548), glucokinase (gk), glucokinase (hexokinase 4) L homeolog (gck.L), glucokinase (hexokinase 4) (gck), BA4487, FGQTL3, GCK, gck-A, GK, Gk, GLK, glk, Gls006, glucokinase, GLUKA, HHF3, hhf3, HK4, hk4, HKIV, hkiv, HXKP, hxkp, LGLK, MODY2, mody2, RNGK2Bezeichner auf Proteinebene für GCK
- ATP:D-hexose 6-phosphotransferase
- HK IV
- glucokinase
- hexokinase D, pancreatic isozyme
- hexokinase type IV
- hexokinase-4
- hexokinase-D
- hexokinase 4
- glucokinase (hexokinase 4, maturity onset diabetes of the young 2)
- HK4
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