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GCK Antikörper (C-Term)

GCK Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB05339 unconjugated
Produktnummer ABIN392391
  • Target Alle GCK Antikörper anzeigen
    GCK (Glucokinase (Hexokinase 4) (GCK))
    Bindungsspezifität
    • 10
    • 9
    • 8
    • 7
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 403-433, C-Term
    Reaktivität
    • 69
    • 31
    • 21
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 65
    • 8
    Kaninchen
    Klonalität
    • 68
    • 5
    Polyklonal
    Konjugat
    • 39
    • 6
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser GCK Antikörper ist unkonjugiert
    Applikation
    • 57
    • 36
    • 34
    • 8
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This GCK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 403-433 amino acids from the C-terminal region of human GCK.
    Klon
    RB05339
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product GCK Primärantikörper
  • Applikationshinweise
    WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    GCK (Glucokinase (Hexokinase 4) (GCK))
    Andere Bezeichnung
    GCK (GCK Produkte)
    Synonyme
    FGQTL3 antikoerper, GK antikoerper, GLK antikoerper, HHF3 antikoerper, HK4 antikoerper, HKIV antikoerper, HXKP antikoerper, LGLK antikoerper, MODY2 antikoerper, Gk antikoerper, Gls006 antikoerper, GCK antikoerper, BA4487 antikoerper, glk antikoerper, hk4 antikoerper, hhf3 antikoerper, hkiv antikoerper, hxkp antikoerper, gck-A antikoerper, mody2 antikoerper, glucokinase antikoerper, GLUKA antikoerper, RNGK2 antikoerper, glucokinase antikoerper, glucokinase (hexokinase 4) L homeolog antikoerper, glucokinase (hexokinase 4) antikoerper, GCK antikoerper, Gck antikoerper, glcK antikoerper, Bphyt_1025 antikoerper, Halhy_6548 antikoerper, gk antikoerper, gck.L antikoerper, gck antikoerper
    Hintergrund
    Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. Alternative splicing of the gene for GCK results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in the gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), also called maturity onset diabetes of the young, type 2 (MODY2), mutations have also been associated with persistent hyperinsulinemic hypoglycemia of infancy (PHHI).
    Molekulargewicht
    52191
    Gen-ID
    2645
    NCBI Accession
    NP_000153, NP_277042, NP_277043
    UniProt
    P35557
    Pathways
    MAPK Signalweg, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process
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