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Glucagon Antikörper

(Glucagon (GCG))
Glucagon is a hormone that plays a crucial role in regulating blood glucose levels in the body. It is primarily produced by the alpha cells of the pancreas. The main function of glucagon is to counteract the actions of insulin, another hormone produced by the pancreas, by stimulating the liver to release glucose into the bloodstream. This process is known as hepatic glucose production. Glucagon acts on the liver to break down glycogen, a stored form of glucose, into glucose molecules, which are then released into the bloodstream. This helps to increase blood glucose levels, especially during periods of fasting or low blood sugar levels.

Glucagon also has other effects on metabolism. It promotes the breakdown of fats in adipose tissue, leading to the release of fatty acids into the bloodstream. It can also stimulate the production of ketone bodies, which are alternative energy sources derived from fat metabolism. Additionally, glucagon can inhibit the synthesis of glycogen and fatty acids, further contributing to the mobilization of stored energy.

Overall, the role of glucagon is to maintain glucose homeostasis in the body by increasing blood glucose levels when they are low. It works in coordination with insulin to regulate blood sugar levels and ensure that they stay within a normal range.

The main applications of anti-Glucagon antibodies include:

  • Immunohistochemistry (IHC): Glucagon antibodies are used in IHC to detect and visualize Glucagon in tissue samples, particularly in pancreatic tissue sections.
  • Immunocytochemistry (ICC): These Glucagon antibodies are also used in ICC to detect and localize Glucagon in cultured cells.
  • Western Blot: Glucagon antibodies can be used in Western blotting techniques to detect Glucagon.
  • ELISA: Enzyme-Linked Immunosorbent Assay (ELISA) can be performed using anti-Glucagon antibodies to quantify the levels of Glucagon in biological samples.
  • Flow Cytometry: Glucagon antibodies can be used in flow cytometry (FACS) to analyze and sort cells based on their Glucagon expression levels.

Gesetzte Filter:

  • Target: Glucagon (GCG)
  • Primary
Catalog no. Produkt Reaktivität Wirt / Klonalität Anwendung Preis & Lieferzeit
ABIN7993386
Glucagon Antikörper (N-Term) (PE) GCG · Primary Antibody Human, Ratte, Maus Kaninchen Polyclonal
  • IHC (Immunohistochemistry: Angegebene Anwendung)
  • IF (Immunofluorescence: Angegebene Anwendung)
1.017,50 € Preis anzeigen
  • 100 μg
Lieferung in 8 bis 12 Werktagen Lieferung nach: Deutschland
ABIN7993387
Glucagon Antikörper (N-Term) (Fluoro647) GCG · Primary Antibody Human, Ratte, Maus Kaninchen Polyclonal
  • IHC (Immunohistochemistry: Angegebene Anwendung)
  • IF (Immunofluorescence: Angegebene Anwendung)
852,50 € Preis anzeigen
  • 100 μg
Lieferung in 8 bis 12 Werktagen Lieferung nach: Deutschland
Primary Antibody
  • IHC (Immunohistochemistry: Angegebene Anwendung)
  • IF (Immunofluorescence: Angegebene Anwendung)
Reaktivität
Human, Ratte, Maus
Wirt
Kaninchen
Klonalität
Polyclonal
Konjugat
PE
Isotyp
IgG
Bindungsspezifität
N-Term
Produktnummer ABIN7993386
1.017,50 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach: Deutschland
Lieferung in 8 bis 12 Werktagen
Primary Antibody
  • IHC (Immunohistochemistry: Angegebene Anwendung)
  • IF (Immunofluorescence: Angegebene Anwendung)
Reaktivität
Human, Ratte, Maus
Wirt
Kaninchen
Klonalität
Polyclonal
Konjugat
Fluoro647
Isotyp
IgG
Bindungsspezifität
N-Term
Produktnummer ABIN7993387
852,50 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach: Deutschland
Lieferung in 8 bis 12 Werktagen

Aktuelle Publikationen für unsere Glucagon Antikörper

Xu, Wang, Guo, Liu, Zhang, Xu, Chen: "Emodin Alleviates Severe Acute Pancreatitis-Associated Acute Lung Injury by Inhibiting the Cold-Inducible RNA-Binding Protein (CIRP)-Mediated Activation of the NLRP3/IL-1β/CXCL1 Signaling." in: Frontiers in pharmacology, Vol. 12, pp. 655372, (2021) (PubMed).

Chen, Ren, Zhou, Deng, Hu, Zhang, Li: "HWL-088, a new potent free fatty acid receptor 1 (FFAR1) agonist, improves glucolipid metabolism and acts additively with metformin in ob/ob diabetic mice." in: British journal of pharmacology, Vol. 177, Issue 10, pp. 2286-2302, (2021) (PubMed).

Huang, Li, Chen, Zhao, Huang, Zhou, Xu: "Identification of Potential Therapeutic Targets and Pathways of Liraglutide Against Type 2 Diabetes Mellitus (T2DM) Based on Long Non-Coding RNA (lncRNA) Sequencing." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 26, pp. e922210, (2020) (PubMed).

Lau, Corrales, Alexander, Mohammadi, Li, Smink, de Vos, Lakey: "Necrostatin-1 supplementation enhances young porcine islet maturation and in vitro function." in: Xenotransplantation, pp. e12555, (2019) (PubMed).

Yang, Yan, Tong, Zhang, Chen, Xue, Wang, Chu, Jin, Li: "Chronic oscillating glucose challenges disarrange innate immune homeostasis to potentiate the variation of neutrophil-lymphocyte ratio in rats with or without hidden diabetes mellitus." in: Diabetes, metabolic syndrome and obesity : targets and therapy, Vol. 11, pp. 277-288, (2018) (PubMed).

Vecchio, Lo Buono, Stabilini, Nigi, Dufort, Geyer, Rancoita, Cugnata, Mandelli, Valle, Leete, Mancarella, Linsley, Krogvold, Herold, Elding Larsson, Richardson, Morgan, Dahl-Jørgensen, Sebastiani et al.: "Abnormal neutrophil signature in the blood and pancreas of presymptomatic and symptomatic type 1 diabetes. ..." in: JCI insight, Vol. 3, Issue 18, (2018) (PubMed).

Lu, Heyne, Dror, Casas, Leonhardt, Boenke, Yang, Sagar, Arrigoni, Dalgaard, Teperino, Enders, Selvaraj, Ruf, Raja, Xie, Boenisch, Orkin, Lynn, Hoffman, Grün, Vavouri, Lempradl, Pospisilik: "The Polycomb-Dependent Epigenome Controls β Cell Dysfunction, Dedifferentiation, and Diabetes." in: Cell metabolism, Vol. 27, Issue 6, pp. 1294-1308.e7, (2018) (PubMed).

Su, Peng, Gong, Liu, Zhang, Lian, Cao, Wu, Liu, Wang, Wang, Jiang: "Antidiabetic drug glyburide modulates depressive-like behavior comorbid with insulin resistance." in: Journal of neuroinflammation, Vol. 14, Issue 1, pp. 210, (2018) (PubMed).

Wang, Tian, Chen, Tan, Xie, Chen, Fu, Chen, Xu, Wei: "Low dose doxycycline decreases systemic inflammation and improves glycemic control, lipid profiles, and islet morphology and function in db/db mice." in: Scientific reports, Vol. 7, Issue 1, pp. 14707, (2017) (PubMed).

Brown, Andrzejewski, Burnside, Schneyer: "Activin Enhances α- to β-Cell Transdifferentiation as a Source For β-Cells In Male FSTL3 Knockout Mice." in: Endocrinology, Vol. 157, Issue 3, pp. 1043-54, (2016) (PubMed).

Aliase für Glucagon Antikörper

glucagon (GCG) Antikörper
glucagon (Gcg) Antikörper
glucagon L homeolog (gcg.L) Antikörper
GCG Antikörper
gcg-A Antikörper
gcg1 Antikörper
GLP-1 Antikörper
GLP1 Antikörper
GLP2 Antikörper
Glu Antikörper
GRPP Antikörper
PPG Antikörper
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