ERCC1 Produkte
(Excision Repair Cross Complementing Polypeptide-1 (ERCC1))
Kategorien
The product of this gene functions in the nucleotide excision repair pathway, and is required for the repair of DNA lesions such as those induced by UV light or formed by electrophilic compounds including cisplatin. The encoded protein forms a heterodimer with the XPF endonuclease (also known as ERCC4), and the heterodimeric endonuclease catalyzes the 5' incision in the process of excising the DNA lesion. The heterodimeric endonuclease is also involved in recombinational DNA repair and in the repair of inter-strand crosslinks. Mutations in this gene result in cerebrooculofacioskeletal syndrome, and polymorphisms that alter expression of this gene may play a role in carcinogenesis. Multiple transcript variants encoding different isoforms have been found for this gene. The last exon of this gene overlaps with the CD3e molecule, epsilon associated protein gene on the opposite strand. [provided by RefSeq, Oct 2009].
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Ausgewählte ERCC1 Kategorien
ERCC1 Antikörper
High quality antibodies with extensive validation data.
ERCC1 ELISA Kits
Reliable ELISA kits for a wide range of species.
ERCC1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene ERCC1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validierungen
- (6)
Kat. Nr.
ABIN733553
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, ELISA, IHC, FACS
Validierungen
- (7)
Kat. Nr.
ABIN7193699
Menge
0.1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
IHC, StM
Validierungen
- (5)
Kat. Nr.
ABIN6939333
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene ERCC1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6955669
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6966615
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Analytical Method
Qualitative Cell ELISA
Validierungen
Kat. Nr.
ABIN1381118
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene ERCC1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7122859
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7122858
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1353027
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren ERCC1 Produkten
: "ERCC1 as predictive biomarker to platinum-based chemotherapy in adrenocortical carcinomas." in: European journal of endocrinology, Vol. 178, Issue 2, pp. 181-188, (2018) (PubMed).: "A novel antibody-based approach to detect the functional ERCC1-202 isoform." in: DNA repair, Vol. 64, pp. 34-44, (2018) (PubMed).
: "The age-related expression decline of ERCC1 and XPF for forensic age estimation: A preliminary study." in: Journal of forensic and legal medicine, Vol. 49, pp. 15-19, (2017) (PubMed).
: "Development and Validation of an ERCC1 Immunohistochemistry Assay for Solid Tumors." in: Archives of pathology & laboratory medicine, Vol. 140, Issue 12, pp. 1397-1403, (2016) (PubMed).
: "Aging asymmetry: systematic survey of changes in age-related biomarkers in the annual fish Nothobranchius guentheri." in: Fish physiology and biochemistry, (2016) (PubMed).
: "Classic biphasic pulmonary blastoma with brain and axillary metastases: a case report with molecular analysis and review of literature." in: International journal of clinical and experimental pathology, Vol. 8, Issue 1, pp. 983-8, (2015) (PubMed).
: "Accumulation of an endogenous tryptophan-derived metabolite in colorectal and breast cancers." in: PLoS ONE, Vol. 10, Issue 4, pp. e0122046, (2015) (PubMed).
: "The clue of a possible etiology about spontaneous regression of hepatocellular carcinoma: a perspective on pathology." in: OncoTargets and therapy, Vol. 8, pp. 395-400, (2015) (PubMed).
: "Primary urinary bladder adenosquamous carcinoma complicated with lower limb deep venous thromboses: a case report." in: International journal of clinical and experimental pathology, Vol. 7, Issue 12, pp. 9032-7, (2015) (PubMed).
: "A phase 2 cooperative group adjuvant trial using a biomarker-based decision algorithm in patients with stage I non-small cell lung cancer (SWOG-0720, NCT00792701)." in: Cancer, Vol. 120, Issue 15, pp. 2343-51, (2014) (PubMed).
Synonyme und alternative Namen zu ERCC1
ERCC excision repair 1, endonuclease non-catalytic subunit (ERCC1), excision repair cross-complementing rodent repair deficiency, complementation group 1 (Ercc1), ERCC excision repair 1, endonuclease non-catalytic subunit (Ercc1), DNA excision repair protein ERCC-1 (CC1G_04546), DNA excision repair protein ERCC-1 (CpipJ_CPIJ013903), DNA excision repair protein ERCC-1 (PITG_13719), ERCC excision repair 1, endonuclease non-catalytic subunit (ercc1), nucleotide repair protein (ERCC1), excision repair cross-complementation group 1 L homeolog (ercc1.L), excision repair cross-complementation group 1 (ercc1), COFS4, Ercc-1, ercc1, RAD10, T12H1.18, T12H1_18, UV20, UVR7, UV REPAIR DEFICIENT 7Bezeichner auf Proteinebene für ERCC1
- DNA excision repair protein ERCC-1
- excision repair 1
- excision repair cross-complementing 1
- excision repair protein
- excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
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