ERG Produkte
(ERG, ETS transcription factor (ERG))
Kategorien
This gene encodes a member of the erythroblast transformation-specific (ETS) family of transcriptions factors. All members of this family are key regulators of embryonic development, cell proliferation, differentiation, angiogenesis, inflammation, and apoptosis. The protein encoded by this gene is mainly expressed in the nucleus. It contains an ETS DNA-binding domain and a PNT (pointed) domain which is implicated in the self-association of chimeric oncoproteins. This protein is required for platelet adhesion to the subendothelium, inducing vascular cell remodeling. It also regulates hematopoesis, and the differentiation and maturation of megakaryocytic cells. This gene is involved in chromosomal translocations, resulting in different fusion gene products, such as TMPSSR2-ERG and NDRG1-ERG in prostate cancer, EWS-ERG in Ewing's sarcoma and FUS-ERG in acute myeloid leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jan 2012].
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Ausgewählte ERG Kategorien
ERG Antikörper
High quality antibodies with extensive validation data.
ERG Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene ERG Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF, IHC (p)
Validierungen
- (5)
Kat. Nr.
ABIN1498076
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, IF, ICC
Validierungen
- (4)
Kat. Nr.
ABIN2854677
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IHC, IF, ICC
Validierungen
- (4)
Kat. Nr.
ABIN6261595
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene ERG Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (1)
- (2)
Kat. Nr.
ABIN2720464
Menge
20 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7122812
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1353056
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren ERG Produkten
: "Analytical platform evaluation for quantification of ERG in prostate cancer using protein and mRNA detection methods." in: Journal of translational medicine, Vol. 13, pp. 54, (2015) (PubMed).: "FZD4 as a mediator of ERG oncogene-induced WNT signaling and epithelial-to-mesenchymal transition in human prostate cancer cells." in: Cancer research, Vol. 70, Issue 17, pp. 6735-45, (2010) (PubMed).
: "Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer." in: Science (New York, N.Y.), Vol. 310, Issue 5748, pp. 644-8, (2005) (PubMed).
Synonyme und alternative Namen zu ERG
ERG, ETS transcription factor (ERG), ERG, ETS transcription factor (Erg), v-ets avian erythroblastosis virus E26 oncogene homolog L homeolog (erg.L), v-ets avian erythroblastosis virus E26 oncogene homolog (erg), v-ets avian erythroblastosis virus E26 oncogene homolog S homeolog (erg.S), ETS transcription factor (Erg), potassium voltage-gated channel subfamily H member 6 (KCNH6), D030036I24Rik, erg, ERG, erg-3, erg_A, erg_E, KCNH2, p55, zgc:103429Bezeichner auf Proteinebene für ERG
- TMPRSS2/ERG fusion
- ets-related
- transcriptional regulator ERG
- transcriptional regulator ERG (transforming protein ERG)
- v-ets avian erythroblastosis virus E26 oncogene related
- v-ets erythroblastosis virus E26 oncogene homolog
- v-ets erythroblastosis virus E26 oncogene like
- avian erythroblastosis virus E-26 (v-ets) oncogene related
- vascular ETS factor
- erg1
- erg gene (erg_E)
- v-ets erythroblastosis virus E26 oncogene homolog (avian)
- transcriptional regulator Erg
- ERG-1
- HERG protein
- eag-related protein 1
- ether-a-go-go-related gene potassium channel 1
- ether-a-go-go-related protein 1
- potassium voltage-gated channel subfamily H member 2
- voltage-gated potassium channel subunit Kv11.1
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