Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
Alle Spezies anzeigen
Weitere Synonyme anzeigen
Wählen Sie die Spezies und Applikation aus
anti-Human NRF2 Antikörper:
anti-Mouse (Murine) NRF2 Antikörper:
anti-Rat (Rattus) NRF2 Antikörper:
Sie gelangen zu unserer vorgefilterten Suche.
Human Polyclonal NRF2 Primary Antibody für IF (p), IHC (p) - ABIN737271
Lee, Hsu, Chang, Kuo, Hsu, Pan: Ankaflavin: a natural novel PPAR? agonist upregulates Nrf2 to attenuate methylglyoxal-induced diabetes in vivo. in Free radical biology & medicine 2012
Show all 19 Pubmed References
Human Polyclonal NRF2 Primary Antibody für IHC (fro), IF (p) - ABIN676673
Lee, Hsu, Hsu, Pan: Dimerumic acid attenuates receptor for advanced glycation endproducts signal to inhibit inflammation and diabetes mediated by Nrf2 activation and promotes methylglyoxal metabolism into d-lactic acid. in Free radical biology & medicine 2013
Show all 17 Pubmed References
Human Polyclonal NRF2 Primary Antibody für ChIP, ICC - ABIN442777
Sullivan, Martinez-Garcia, Nguyen, Mullen, Dufour, Sudarshan, Licht, Deberardinis, Chandel: The proto-oncometabolite fumarate binds glutathione to amplify ROS-dependent signaling. in Molecular cell 2013
Show all 4 Pubmed References
Human Polyclonal NRF2 Primary Antibody für IHC, IHC (p) - ABIN4340688
Suchocki, Misiewicz-Krzemińska, Skupińska, Niedźwiecka, Lubelska, Fijałek, Kasprzycka-Guttman: Selenitetriglicerydes affect CYP1A1 and QR activity by involvement of reactive oxygen species and Nrf2 transcription factor. in Pharmacological reports : PR 2010
Show all 3 Pubmed References
Human Polyclonal NRF2 Primary Antibody für IHC, ELISA - ABIN1584873
Bagul, Middela, Matapally, Padiya, Bastia, Madhusudana, Reddy, Chakravarty, Banerjee: Attenuation of insulin resistance, metabolic syndrome and hepatic oxidative stress by resveratrol in fructose-fed rats. in Pharmacological research : the official journal of the Italian Pharmacological Society 2012
Show all 2 Pubmed References
Human Polyclonal NRF2 Primary Antibody für IHC (p), WB - ABIN3043888
Wang, Du, Duan, Guo, Sun, Liu: Inhibiting heme oxygenase-1 attenuates rat liver fibrosis by removing iron accumulation. in World journal of gastroenterology : WJG 2013
Show all 2 Pubmed References
Rat (Rattus) Polyclonal NRF2 Primary Antibody für ICC, IHC - ABIN1869445
Baluchnejadmojarad, Zeinali, Roghani: Scutellarin alleviates lipopolysaccharide-induced cognitive deficits in the rat: Insights into underlying mechanisms. in International immunopharmacology 2017
Human Monoclonal NRF2 Primary Antibody für IF, ELISA - ABIN518315
Lindl, Jordan-Sciutto: Examining the endogenous antioxidant response through immunofluorescent analysis of Nrf2 in tissue. in Methods in molecular biology (Clifton, N.J.) 2008
Human Monoclonal NRF2 Primary Antibody für IHC, ELISA - ABIN1724931
Sandford, Malhotra, Boezen, Siedlinski, Postma, Wong, Akhabir, He, Connett, Anthonisen, Paré, Biswal: NFE2L2 pathway polymorphisms and lung function decline in chronic obstructive pulmonary disease. in Physiological genomics 2012
Knockdown of Nrf2 paralogs perturbed glutathione redox state in zebrafish embryo. Nrf2 alone is not essential for the response and recovery of glutathione to oxidative insults.
nrf2a modulates the embryonic response to perfluorooctanesulfonic acid (PFOS), and that PPAR (zeige PPARA Antikörper) signaling may play a role in the embryonic adaptive response to PFOS.
These results suggest that alpha,beta-unsaturated carbonyl entity and catechol moiety of 6S derivatives may react with the cysteine residues of Keap1 (zeige KEAP1 Antikörper), disrupting the Keap1 (zeige KEAP1 Antikörper)-Nrf2 complex, thereby liberating and activating Nrf2. Our findings of natural product-derived Nrf2 activators lead to design options of potent Nrf2 activators for further optimization.
These data suggest that EC from the Tripterygium wilfordii stem extract could diminish tau-GFP-induced neuronal death through the activation of Nrf2.
we concluded that Nrf2 plays a fundamental and conserved role in protection against acute sodium arsenite toxicity
Coptisine exerted its antioxidant activity against AAPH-induced toxicity involving in activating Akt (zeige AKT1 Antikörper) and JNK (zeige MAPK8 Antikörper)/Nrf2/NQO1 (zeige NQO1 Antikörper) pathway.
Bach1 (zeige BACH1 Antikörper) regulates the liver specificity and transience of the Nrf2a-dependent induction of hmox1a and that heme mediates this regulation through Bach1 (zeige BACH1 Antikörper) inhibition based on its level in each tissue.
The Bach1b-MafK heterodimer represses the zymogen promoters, whereas the Nrf2a-MafK heterodimer activates them.
The expression of nrf genes varies temporally throughout development and nrf genes are induced following a pro-oxidant exposure and are potentially cross-regulated by gene family members Nrf2a and Nrf2b.
oxidative stress is an important mechanism of Cd-mediated injury in the zebrafish olfactory system; the Nrf2 pathway plays a protective role against cellular oxidative damage and is important in maintaining zebrafish olfactory function.
These findings suggest that bronchiolar epithelial cells and macrophages up-regulate Nrf2 expression early in the course of infection, which results in increased expression of HO-1 (zeige HMOX1 Antikörper) within these cells.
the survival and developmental competence of embryos cultured under oxidative stress are associated with activity of the NRF2-mediated oxidative stress response pathway during bovine pre-implantation embryo development.
investigation of molecular mechanisms of microvascular complications in diabetes/hyperglycemia: Nrf2 is involved in regulation of HO-1 (zeige HMOX1 Antikörper) gene expression in aortic endothelial cells by advanced glycation end products
Lack of Nrf2 enhances susceptibility to mycotoxin-induced kidney disease.
The effects of ochratoxin A on the nuclear translocation and transactivation of the transcription factor Nrf2 as well as mRNA levels of Nrf2 target genes are reported.
Nrf2 (zeige GABPA Antikörper) overexpression was associated with tumor size, histological grade, and metastasis in gastric cancer patients.
Data (including data from studies using tissues/cells from transgenic mice) suggest that ChREBPalpha up-regulates expression and activity of NRF2 (zeige GABPA Antikörper), initiating mitochondrial biogenesis in beta-cells; induction of NRF2 (zeige GABPA Antikörper) is required for ChREBPalpha-mediated effects and for glucose-stimulated beta-cell proliferation. [ChREBP (zeige MLXIPL Antikörper) = carbohydrate-responsive element-binding protein (zeige MLXIPL Antikörper)]
The NFE2L2 promotor variant rs6721961 may be protective against hearing loss in cisplatin-receiving cancer patients by affecting NFE2L2 gene expression.
Following arachidin-1 pretreatment, the H2O2-induced generation of reactive oxygen species was reduced. Therefore, the present results indicate that arachidin-1 suppresses TNF-alpha (zeige TNF Antikörper)-induced inflammation in ECs through the upregulation of Nrf-2 (zeige GABPA Antikörper)-related phase II enzyme expression.
In the present review we briefly introduce the Nrf2 (zeige GABPA Antikörper)-Keap1 (zeige KEAP1 Antikörper) system and describe Nrf2 (zeige GABPA Antikörper) functions, illustrate the Nrf2 (zeige GABPA Antikörper)-NF-kappaB (zeige NFKB1 Antikörper) cross-talk, and highlight the effects of the Nrf2 (zeige GABPA Antikörper)-Keap1 (zeige KEAP1 Antikörper) system in the physiology and pathophysiology of striated (zeige NSDHL Antikörper) muscle tissue taking into account its role(s) in oxidative stress and reductive stress
In light of a pivotal role of NRF2 (zeige GABPA Antikörper) and BACH1 (zeige BACH1 Antikörper) in response to oxidative stress and regulation of HO-1 (zeige HMOX1 Antikörper), we examined if smoke-induced HO-1 (zeige HMOX1 Antikörper) expression is modulated through the NRF2 (zeige GABPA Antikörper)/BACH1 (zeige BACH1 Antikörper) axis. We demonstrated that smoke causes significant nuclear translocation of NRF2 (zeige GABPA Antikörper), but only a slight decrease in nuclear BACH1 (zeige BACH1 Antikörper).
Study found that NRF2 (zeige GABPA Antikörper) expression level was significantly of down-regulated in hepatic ischemia-reperfusion (HIR (zeige KCNJ4 Antikörper)) model.
Enhanced BRAF (zeige BRAF Antikörper)-mediated NRF2 (zeige GABPA Antikörper) gene transcription and Histone Acetyltransferases-mediated NRF2 (zeige GABPA Antikörper) protein acetylation contributes to ABCC1 (zeige ABCC1 Antikörper)-mediated chemoresistance and glutathione-mediated survival in acquired topoisomerase II (zeige TOP2 Antikörper) poison-resistant cancer cells.
Respiratory syncytial virus induces NRF2 (zeige GABPA Antikörper) degradation through a PML (zeige PML Antikörper)-RNF4 (zeige RNF4 Antikörper) pathway.
Results show that NRF2 (zeige GABPA Antikörper) activity is positively regulated by miR (zeige MLXIP Antikörper)-432-3p through downregulation of KEAP1 (zeige KEAP1 Antikörper) inducing its stability in squamous cell carcinoma.
We identified that Nrf2 activation inhibited NLRP3 (zeige NLRP3 Antikörper) inflammasome expression and subsequent IL-1beta (zeige IL1B Antikörper) generation. Furthermore, the activation of NLRP3 (zeige NLRP3 Antikörper) inflammasome was sensitive to the reactive oxygen species (ROS (zeige ROS1 Antikörper)) level and Nrf2 could decrease the production of ROS (zeige ROS1 Antikörper).
Data (including data from studies using tissues/cells from transgenic mice) suggest that ChREBPalpha up-regulates expression and activity of Nrf2, initiating mitochondrial biogenesis in beta-cells; induction of Nrf2 is required for ChREBPalpha-mediated effects and for glucose-stimulated beta-cell proliferation. [ChREBP (zeige MLXIPL Antikörper) = carbohydrate-responsive element-binding protein (zeige MLXIPL Antikörper)]
Nrf2 deficiency promoted Th17 differentiation and function during Lupus nephritis development.
Data suggest a clear link between Nrf2 and AD-mediated cognitive decline and further strengthen the connection between Nrf2 and AD.
These results suggested that schisandrin A has a protective effect against LPS (zeige TLR4 Antikörper)-induced inflammatory and oxidative responses in RAW 264.7 cells by inhibiting the NF-kappaB (zeige NFKB1 Antikörper), MAPK (zeige MAPK1 Antikörper) and PI3K/Akt (zeige AKT1 Antikörper) pathways; these effects are mediated, at least in part, by the activation of the Nrf2/HO-1 (zeige HMOX1 Antikörper) pathway
Nrf2-null mice displayed high levels of oxidative stress and were inherently vulnerable to depression, but this phenotype was reversed by treatment with antioxidants. Results reveal a novel role for BDNF (zeige BDNF Antikörper) in controlling redox homeostasis and provide a mechanistic explanation for post-stress vulnerability to depression while suggesting ways to reverse it.
results suggest that miR (zeige MLXIP Antikörper)-144-3p contributes to OGD (zeige FGFR1 Antikörper)/R-induced neuronal injury in vitro through negatively regulating Brg1 (zeige SMARCA4 Antikörper)/Nrf2/ARE signaling.
Study provides evidence that sirtuin 6 (SIRT6 (zeige SIRT6 Antikörper)) can protect the brain from cerebral cerebral ischemia/reperfusion injury by suppressing oxidative stress via nuclear factor (erythroid-derived 2)-like 2 activation. Thus, SIRT6 (zeige SIRT6 Antikörper) may serve as a potential therapeutic target for ischemic stroke.
Rosiglitazone Regulates TLR4 (zeige TLR4 Antikörper) and Rescues HO-1 (zeige HMOX1 Antikörper) and NRF2 Expression in Myometrial and Decidual Macrophages in Inflammation-Induced Preterm Birth.
evidence for Nrf2 dependent regulation of a subset of cardiac miRNAs in the basal myocardium.
This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters\; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been found for this gene.
, nuclear factor (erythroid-derived 2)-like 2
, nuclear factor erythroid 2-related factor 2
, NF-E2-related factor 2
, NFE2-related factor 2
, nuclear factor, erythroid derived 2, like 2
, nuclear factor erythroid-derived 2-like 2
, nuclear factor erythroid 2-like 2