E2F5 Produkte
(E2F5)
Kategorien
The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionarily conserved domains that are present in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein is differentially phosphorylated and is expressed in a wide variety of human tissues. It has higher identity to E2F4 than to other family members. Both this protein and E2F4 interact with tumor suppressor proteins p130 and p107, but not with pRB. Alternative splicing results in multiple variants encoding different isoforms. [provided by RefSeq, Jul 2008].
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Ausgewählte E2F5 Kategorien
E2F5 Antikörper
High quality antibodies with extensive validation data.
E2F5 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene E2F5 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, FACS, IHC (p)
Validierungen
- (1)
- (3)
Kat. Nr.
ABIN652951
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human, Rat
Applikation
WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro)
Validierungen
- (1)
- (2)
Kat. Nr.
ABIN733673
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IHC
Validierungen
- (2)
Kat. Nr.
ABIN7006970
Menge
20 μL
Datenblatt
Datenblatt
Empfohlene E2F5 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Analytical Method
Qualitative DNA-Binding ELISA
Validierungen
Kat. Nr.
ABIN5648569
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene E2F5 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3079243
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3122979
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN2719897
Menge
50 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren E2F5 Produkten
: "The Effects of miR-20a on p21: Two Mechanisms Blocking Growth Arrest in TGF-β-Responsive Colon Carcinoma." in: Journal of cellular physiology, Vol. 230, Issue 12, pp. 3105-14, (2015) (PubMed).: "NFkB is activated by multiple mechanisms in hairy cell leukemia." in: Genes, chromosomes & cancer, Vol. 54, Issue 7, pp. 418-32, (2015) (PubMed).
: "Sj7170, a unique dual-function peptide with a specific ?-chymotrypsin inhibitory activity and a potent tumor-activating effect from scorpion venom." in: The Journal of biological chemistry, Vol. 289, Issue 17, pp. 11667-80, (2014) (PubMed).
: "Analysis of genetic aberrations on chromosomal region 8q21-24 identifies E2F5 as an oncogene with copy number gain in prostate cancer." in: Medical oncology (Northwood, London, England), Vol. 30, Issue 1, pp. 465, (2013) (PubMed).
Synonyme und alternative Namen zu E2F5
E2F transcription factor 5 (E2f5), E2F transcription factor 5 (e2f5), E2F transcription factor 5 (E2F5), AU024671, cb735, E2F-5, E2f-5, E2F4, zgc:111879Bezeichner auf Proteinebene für E2F5
- transcription factor E2F5
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