Dystroglycan Produkte
(Dystroglycan 1 (DAG1))
Kategorien
Dystroglycan is a laminin binding component of the dystrophin-glycoprotein complex which provides a linkage between the subsarcolemmal cytoskeleton and the extracellular matrix. Dystroglycan 1 is a candidate gene for the site of the mutation in autosomal recessive muscular dystrophies. The dramatic reduction of dystroglycan 1 in Duchenne muscular dystrophy leads to a loss of linkage between the sarcolemma and extracellular matrix, rendering muscle fibers more susceptible to necrosis. Dystroglycan also functions as dual receptor for agrin and laminin-2 in the Schwann cell membrane. The muscle and nonmuscle isoforms of dystroglycan differ by carbohydrate moieties but not protein sequence. Alternative splicing results in multiple transcript variants all encoding the same protein.[provided by RefSeq, Apr 2010].
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Ausgewählte Dystroglycan Kategorien
Dystroglycan Antikörper
High quality antibodies with extensive validation data.
Dystroglycan ELISA Kits
Reliable ELISA kits for a wide range of species.
Dystroglycan Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene Dystroglycan Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, IHC (p)
Validierungen
- (5)
Kat. Nr.
ABIN658022
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p), ICC, IF
Validierungen
- (1)
- (4)
Kat. Nr.
ABIN2856020
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Mouse
Applikation
WB, IHC, IP, ICC
Validierungen
- (3)
Kat. Nr.
ABIN7434920
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene Dystroglycan ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Various Species
Analytical Method
Quantitative Competition ELISA
Validierungen
- (4)
- (1)
Kat. Nr.
ABIN6955481
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6955482
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6955483
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene Dystroglycan Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (2)
- (1)
Kat. Nr.
ABIN1351078
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7122728
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Insect Cells
Validierungen
- (1)
Kat. Nr.
ABIN3092032
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren Dystroglycan Produkten
: "Bouchardatine analogue alleviates non-alcoholic hepatic fatty liver disease/non-alcoholic steatohepatitis in high-fat fed mice by inhibiting ATP synthase activity." in: British journal of pharmacology, Vol. 176, Issue 16, pp. 2877-2893, (2020) (PubMed).: "The Ying and Yang of Adenosine A1 and A2A Receptors on ERK1/2 Activation in a Rat Model of Global Cerebral Ischemia Reperfusion Injury." in: Molecular neurobiology, Vol. 55, Issue 2, pp. 1284-1298, (2019) (PubMed).
: "Low wnt/β-catenin signaling determines leaky vessels in the subfornical organ and affects water homeostasis in mice." in: eLife, Vol. 8, (2019) (PubMed).
: "Detection of variants in dystroglycanopathy-associated genes through the application of targeted whole-exome sequencing analysis to a large cohort of patients with unexplained limb-girdle muscle ..." in: Skeletal muscle, Vol. 8, Issue 1, pp. 23, (2018) (PubMed).
: "PEDF protects cardiomyocytes by promoting FUNDC1‑mediated mitophagy via PEDF-R under hypoxic condition." in: International journal of molecular medicine, Vol. 41, Issue 6, pp. 3394-3404, (2018) (PubMed).
: "Friedreich Ataxia: Developmental Failure of the Dorsal Root Entry Zone." in: Journal of neuropathology and experimental neurology, Vol. 76, Issue 11, pp. 969-977, (2017) (PubMed).
: "Isolation and characterization of neural stem cells from dystrophic mdx mouse." in: Experimental cell research, Vol. 343, Issue 2, pp. 190-207, (2016) (PubMed).
: "Pigment Epithelium-Derived Factor (PEDF) Improves Ischemic Cardiac Functional Reserve Through Decreasing Hypoxic Cardiomyocyte Contractility Through PEDF Receptor (PEDF-R)." in: Journal of the American Heart Association, Vol. 5, Issue 7, (2016) (PubMed).
: "A High-Throughput Assay for the Detection of α-Dystroglycan N-Terminus in Human Uterine Fluid to Determine Uterine Receptivity." in: Journal of biomolecular screening, Vol. 21, Issue 4, pp. 408-13, (2016) (PubMed).
: "Aryl Hydrocarbon Receptor Plays Protective Roles against High Fat Diet (HFD)-induced Hepatic Steatosis and the Subsequent Lipotoxicity via Direct Transcriptional Regulation of Socs3 Gene Expression." in: The Journal of biological chemistry, Vol. 291, Issue 13, pp. 7004-16, (2016) (PubMed).
Synonyme und alternative Namen zu Dystroglycan
DystroGlycaN (dgn-1), dystroglycan 1 L homeolog (dag1.L), DystroGlycaN (dgn-2), DystroGlycaN (dgn-3), dystroglycan 1 (DAG1), dystroglycan 1 S homeolog (dag1.S), dystroglycan 1 (Dag1), dystroglycan 1 (dag1), Dystroglycan (Dg), dystroglycan (LOC408826), clusterin (Clu), lymphocyte antigen 6 complex (Ly6), 156DAG, 156dag, A3a, a3a, AGRNR, agrnr, Ala-1, APOJ, atu, CG18250, CLI, CT41273, D9Wsu13e, DAG, dag, dag1, DAG1, dg, DG, dgn, DmDG, Dmel\\CG18250, Dp71, Dp427, dys, GB14967, H9/25, LOC398500, Ly-6, Ly-27, Ly27, MDDGC7, MDDGC9, MGC53537, RAB7, RATTRPM2B, SGP-2, SGP2, SP-40, SP40, TRPM-2, Trpm2, TRPM2B, Trpmb, wu:fb83d06, wu:fi25f06, wu:fi37b08, zgc:109786Bezeichner auf Proteinebene für Dystroglycan
- DystroGlycaN family member (dgn-1)
- dystroglycan
- DystroGlycaN family member (dgn-2)
- DystroGlycaN family member (dgn-3)
- dystrophin-associated glycoprotein 1
- dystroglycan 1
- dystroglycan 1 (dystrophin-associated glycoprotein 1)
- RAB7, member RAS oncogene family
- glycine cleavage system T-protein
- alpha-dystroglycan
- beta-dystroglycan
- dystrophin associated glycoprotein 1
- CG18250-PA
- CG18250-PB
- CG18250-PC
- CG18250-PD
- Dg-PA
- Dg-PB
- Dg-PC
- Dg-PD
- atsugari
- dystroglycan-like
- dimeric acid glycoprotein
- sulfated glycoprotein 2
- testosterone repressed prostate message 2
- testosterone-repressed prostate message
- testostrone-repressed prostate message 2
- dystrophin-associated glycoprote
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