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E2F4 Produkte

(E2F Transcription Factor 4, P107/p130-Binding, E2F4)

Kategorien

The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein binds to all three of the tumor suppressor proteins pRB, p107 and p130, but with higher affinity to the last two. It plays an important role in the suppression of proliferation-associated genes, and its gene mutation and increased expression may be associated with human cancer. [provided by RefSeq, Jul 2008].

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Ausgewählte E2F4 Kategorien

E2F4 Antikörper

High quality antibodies with extensive validation data.

E2F4 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene E2F4 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
ReaktivitätHuman, Mouse, Rat
ApplikationELISA, IHC (p), WB
Validierungen
  • collections(5)
Kat. Nr.ABIN3187838
Menge100 μL
ReaktivitätHuman, Mouse, Rat
ApplikationIHC (p), WB
Validierungen
  • collections(4)
Kat. Nr.ABIN4886566
Menge100 μg
ReaktivitätHuman, Monkey, Mouse, Rat
ApplikationELISA, ICC, IF, IHC, WB
Validierungen
  • collections(4)
Kat. Nr.ABIN6261411
Menge100 μL

Empfohlene E2F4 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
ReaktivitätHuman
Analytical MethodQuantitative Sandwich ELISA
Validierungen
Kat. Nr.ABIN6216586
Menge96 tests

Empfohlene E2F4 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
ReaktivitätHuman
SourceInsect Cells
Validierungen
  • collections(1)
Kat. Nr.ABIN3092278
Menge1 mg
ReaktivitätMouse
SourceInsect Cells
Validierungen
  • collections(1)
Kat. Nr.ABIN3126568
Menge1 mg
ReaktivitätHuman
SourceWheat germ
Validierungen
  • collections(1)
Kat. Nr.ABIN1352239
Menge10 μg

Neueste Publikationen zu unseren E2F4 Produkten

Kanakkanthara, Huntoon, Hou, Zhang, Heinzen, OBrien, Oberg, John Weroha, Kaufmann, Karnitz: "ZC3H18 specifically binds and activates the BRCA1 promoter to facilitate homologous recombination in ovarian cancer." in: Nature communications, Vol. 10, Issue 1, pp. 4632, 2019 (PubMed). Von den Autoren verwendete Methode: Western Blotting (WB) (Probematerial (Species): Human).

Morillo, Abanto, Román, Frade: "Nerve growth factor-induced cell cycle reentry in newborn neurons is triggered by p38MAPK-dependent E2F4 phosphorylation." in: Molecular and cellular biology, Vol. 32, Issue 14, pp. 2722-37, 2012 (PubMed).

Zhu, Khozoie, Bility, Ferry, Blazanin, Glick, Gonzalez, Peters: "Peroxisome proliferator-activated receptor β/δ cross talks with E2F and attenuates mitosis in HRAS-expressing cells." in: Molecular and cellular biology, Vol. 32, Issue 11, pp. 2065-82, 2012 (PubMed).

Synonyme und alternative Namen zu E2F4

E2F transcription factor 4 (E2F4), E2F transcription factor 4 (E2f4), E2F transcription factor 4 S homeolog (e2f4.S), E2F transcription factor 4 (e2f4), 2010111M04Rik, AI427446, E2F-4, e2f-4, E2F4, fb72f07, wu:fb72f07, wu:fe05f06, zgc:63815

Gen-IDs für verschiedene Spezies

GENE ID SPEZIES
1874 Homo sapiens
104394 Mus musculus
446541 Xenopus laevis
454158 Pan troglodytes
525428 Bos taurus
611243 Canis lupus familiaris
696864 Macaca mulatta
769430 Gallus gallus
100038079 Xenopus (Silurana) tropicalis
100600930 Nomascus leucogenys
100360427 Rattus norvegicus
100522677 Sus scrofa
406741 Danio rerio
100735380 Cavia porcellus

Bezeichner auf Proteinebene für E2F4

  • p107/p130-binding protein
  • transcription factor E2F4
  • E2F-4
  • E2F transcription factor 4, p107/p130-binding
  • E2F transcription factor 4
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