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E2F6 Produkte

(E2F Transcription Factor 6 (E2F6))

Kategorien

This gene encodes a member of the E2F transcription factor protein family. E2F family members play a crucial role in control of the cell cycle and of the action of tumor suppressor proteins. They are also a target of the transforming proteins of small DNA tumor viruses. Many E2F proteins contain several evolutionarily conserved domains: a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. The encoded protein of this gene is atypical because it lacks the transactivation and tumor suppressor protein association domains. It contains a modular suppression domain and is an inhibitor of E2F-dependent transcription. The protein is part of a multimeric protein complex that contains a histone methyltransferase and the transcription factors Mga and Max. Multiple transcript variants have been reported for this gene, but it has not been clearly demonstrated that they encode valid isoforms. [provided by RefSeq, Jul 2008].

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Ausgewählte E2F6 Kategorien

E2F6 Antikörper

High quality antibodies with extensive validation data.

E2F6 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene E2F6 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, IHC, ELISA, IF, ICC
Validierungen
  • (1)
  • (4)
Kat. Nr. ABIN6261413
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IF, IP, ChIP
Validierungen
  • (4)
Kat. Nr. ABIN6139903
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IF, IP, ChIP
Validierungen
  • (4)
Kat. Nr. ABIN1679632
Menge 100 μg
Datenblatt Datenblatt

Empfohlene E2F6 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1352242
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
  • (1)
Kat. Nr. ABIN3079106
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Tobacco (Nicotiana tabacum)
Validierungen
  • (1)
Kat. Nr. ABIN3131804
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren E2F6 Produkten

Ai, Zhang, Gao, Qin, Zhong, Gu, Li, Qiao, Tian, Cui, Yang, Bi, Xiao, Chen, Liu, Zhou, Sun, Yang: "Sesquiterpene binding Gly-Leu-Ser/Lys-"co-adaptation pocket" to inhibit lung cancer cell epithelial-mesenchymal transition." in: Oncotarget, Vol. 8, Issue 41, pp. 70192-70203, (2018) (PubMed).

McLaughlin-Drubin, Huh, Münger: "Human papillomavirus type 16 E7 oncoprotein associates with E2F6." in: Journal of virology, Vol. 82, Issue 17, pp. 8695-705, (2008) (PubMed).

Xu, Bieda, Jin, Rabinovich, Oberley, Green, Farnham: "A comprehensive ChIP-chip analysis of E2F1, E2F4, and E2F6 in normal and tumor cells reveals interchangeable roles of E2F family members." in: Genome research, Vol. 17, Issue 11, pp. 1550-61, (2007) (PubMed).

Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

Synonyme und alternative Namen zu E2F6

E2F transcription factor 6 (E2F6), E2F transcription factor 6 (E2f6), AI462434, E2F-6, E2F6b, EMA

Bezeichner auf Proteinebene für E2F6

  • E2F transcription factor 6
  • transcription factor E2F6
  • E2F-6
  • E2F-binding site-modulating activity protein
  • transcriptional repressor E2F6
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