DYST Protein (AA 1-195, partial) (His tag)
Kurzübersicht für DYST Protein (AA 1-195, partial) (His tag) (ABIN5714422)
Target
Protein-Typ
Spezies
Quelle
Applikation
Reinheit
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Proteineigenschaft
- AA 1-195, partial
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Aufreinigungstag / Konjugat
- Dieses DYST Protein ist gelabelt mit His tag.
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Verwendungszweck
- Recombinant Human Dystonin(DST),partial
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Sequenz
- MHSSSYSYRS SDSVFSNTTS TRTSLDSNEN LLLVHCGPTL INSCISFGSE SFDGHRLEML QQIANRVQRD SVICEDKLIL AGNALQSDSK RLESGVQFQN EAEIAGYILE CENLLRQHVI DVQILIDGKY YQADQLVQRV AKLRDEIMAL RNECSSVYSK GRILTTEQTK LMISGITQSL NSGFAQTLHP SLTSG
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Produktmerkmale
- N-terminal 6xHis-tagged
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.1-2 mg/mL
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Buffer
- Tris-based buffer50 % glycerol
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
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Haltbarkeit
- 6-12 months
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- DYST (Dystocia (Maternal) (DYST))
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Andere Bezeichnung
- DYST
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Hintergrund
- Cytoskeletal linker protein. Acts as an integrator of intermediate filaments, actin and microtubule cytoskeleton networks. Required for anchoring either intermediate filaments to the actin cytoskeleton in neural and muscle cells or keratin-containing intermediate filaments to hidesmosomes in epithelial cells. The proteins may self-aggregate to form filaments or a two-dimensional mesh.Isoform 3: plays a structural role in the assbly of hidesmosomes of epithelial cells, anchors keratin-containing intermediate filaments to the inner plaque of hidesmosomes. Required for the regulation of keratinocyte polarity and motility, mediates integrin ITGB4 regulation of RAC1 activity.Isoform 6: required for bundling actin filaments around the nucleus.Isoform 7: regulates the organization and stability of the microtubule network of sensory neurons to allow axonal transport.
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Molekulargewicht
- 25.1 kDa
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Gen-ID
- 667
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UniProt
- Q03001
Target
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