DOT1L Produkte
(DOT1-Like, Histone H3 Methyltransferase (S. Cerevisiae) (DOT1L))
Kategorien
The protein encoded by this gene is a histone methyltransferase that methylates lysine-79 of histone H3. It is inactive against free core histones, but shows significant histone methyltransferase activity against nucleosomes. [provided by RefSeq, Aug 2011].
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Ausgewählte DOT1L Kategorien
DOT1L Antikörper
High quality antibodies with extensive validation data.
DOT1L ELISA Kits
Reliable ELISA kits for a wide range of species.
DOT1L Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene DOT1L Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF
Validierungen
- (1)
- (4)
Kat. Nr.
ABIN566567
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC
Validierungen
- (3)
Kat. Nr.
ABIN7155530
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
IHC (p)
Validierungen
- (2)
- (1)
Kat. Nr.
ABIN6243177
Menge
400 μL
Datenblatt
Datenblatt
Empfohlene DOT1L ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6955450
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6955451
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene DOT1L Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1351915
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (2)
Kat. Nr.
ABIN2669718
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7317542
Menge
50 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren DOT1L Produkten
: "miR-133b suppresses colorectal cancer cell stemness and chemoresistance by targeting methyltransferase DOT1L." in: Experimental cell research, Vol. 385, Issue 1, pp. 111597, (2019) (PubMed).: "An epigenetic regulator-related score (EpiScore) predicts survival in patients with diffuse large B cell lymphoma and identifies patients who may benefit from epigenetic therapy." in: Oncotarget, Vol. 9, Issue 27, pp. 19079-19099, (2018) (PubMed).
: "2D-DIGE proteomic analysis of vastus lateralis from COPD patients with low and normal fat free mass index and healthy controls." in: Respiratory research, Vol. 18, Issue 1, pp. 81, (2018) (PubMed).
: "Copy-number variation and protein expression of DOT1L in pancreatic adenocarcinoma as a potential drug target." in: Molecular and clinical oncology, Vol. 6, Issue 5, pp. 639-642, (2017) (PubMed).
: "Functional interdependence of BRD4 and DOT1L in MLL leukemia. ..." in: Nature structural & molecular biology, Vol. 23, Issue 7, pp. 673-81, (2016) (PubMed).
: "Incidence of methylated histones H3K4 and H3K79 in cat germinal vesicles is regulated by specific nuclear factors at the acquisition of developmental competence during the folliculogenesis." in: Journal of assisted reproduction and genetics, Vol. 33, Issue 6, pp. 783-94, (2016) (PubMed).
: "Histone methyltransferase DOT1L drives recovery of gene expression after a genotoxic attack." in: PLoS genetics, Vol. 9, Issue 7, pp. e1003611, (2013) (PubMed).
: "Polycomb eviction as a new distant enhancer function." in: Genes & development, Vol. 25, Issue 15, pp. 1583-8, (2011) (PubMed).
: "A novel disrupter of telomere silencing 1-like (DOT1L) interaction is required for signal transducer and activator of transcription 1 (STAT1)-activated gene expression." in: The Journal of biological chemistry, Vol. 286, Issue 48, pp. 41195-204, (2011) (PubMed).
: "DOT1L regulates dystrophin expression and is critical for cardiac function." in: Genes & development, Vol. 25, Issue 3, pp. 263-74, (2011) (PubMed).
Synonyme und alternative Namen zu DOT1L
histone-lysine N-methyltransferase, H3 lysine-79 specific (LOC100116648), DOT1 like histone lysine methyltransferase (DOT1L), histone methyltransferase (DOT1), DOT1 like histone lysine methyltransferase (Dot1l), DOT1-like, histone H3 methyltransferase (S. cerevisiae) (Dot1l), A630076O07, AW907654, DOT1, Dot1, DOT1L, KMT4, mDot1, NV11307Bezeichner auf Proteinebene für DOT1L
- histone-lysine N-methyltransferase, H3 lysine-79 specific
- DOT1-like, histone H3 methyltransferase (S. cerevisiae)
- histone-lysine N-methyltransferase, H3 lysine-79 specific-like
- possible nucleosomal histone methylase
- DOT1-like protein
- DOT1-like, histone H3 methyltransferase
- H3-K79-HMTase
- histone H3-K79 methyltransferase
- histone methyltransferase DOT1L
- lysine N-methyltransferase 4
- DOT1-like histone H3 methyltransferase
- histone H3 methyltransferase DOT1
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