DISC1 Produkte
(Disrupted in Schizophrenia 1 (DISC1))
Kategorien
This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1\;11)(q42.1\;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].
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Ausgewählte DISC1 Kategorien
DISC1 Antikörper
High quality antibodies with extensive validation data.
DISC1 ELISA Kits
Reliable ELISA kits for a wide range of species.
DISC1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene DISC1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (7)
Kat. Nr.
ABIN7439720
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF
Validierungen
- (5)
Kat. Nr.
ABIN7266799
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, IHC
Validierungen
- (3)
Kat. Nr.
ABIN7260711
Menge
200 μL
Datenblatt
Datenblatt
Empfohlene DISC1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Analytical Method
Validierungen
Kat. Nr.
ABIN1129954
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Validierungen
Kat. Nr.
ABIN1129955
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Validierungen
Kat. Nr.
ABIN1129956
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene DISC1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3092106
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3136109
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7405693
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren DISC1 Produkten
: "Disrupted in schizophrenia 1 modulates medial prefrontal cortex pyramidal neuron activity through cAMP regulation of transient receptor potential C and small-conductance K+ channels." in: Biological psychiatry, Vol. 76, Issue 6, pp. 476-85, (2014) (PubMed).: "Disrupted-in-Schizophrenia 1 (DISC1) is necessary for the correct migration of cortical interneurons." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, Issue 2, pp. 738-45, (2012) (PubMed).
: "Elucidating the relationship between DISC1, NDEL1 and NDE1 and the risk for schizophrenia: evidence of epistasis and competitive binding." in: Human molecular genetics, Vol. 17, Issue 16, pp. 2462-73, (2008) (PubMed).
: "DISC1 regulates the transport of the NUDEL/LIS1/14-3-3epsilon complex through kinesin-1." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 27, Issue 1, pp. 15-26, (2007) (PubMed).
: "Disrupted-In-Schizophrenia 1 regulates integration of newly generated neurons in the adult brain." in: Cell, Vol. 130, Issue 6, pp. 1146-58, (2007) (PubMed).
: "Inhibition of NUDEL (nuclear distribution element-like)-oligopeptidase activity by disrupted-in-schizophrenia 1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 10, pp. 3828-33, (2005) (PubMed).
: "DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling." in: Science (New York, N.Y.), Vol. 310, Issue 5751, pp. 1187-91, (2005) (PubMed).
: "Disrupted in Schizophrenia 1 and Nudel form a neurodevelopmentally regulated protein complex: implications for schizophrenia and other major neurological disorders." in: Molecular and cellular neurosciences, Vol. 25, Issue 1, pp. 42-55, (2004) (PubMed).
: "Disrupted in schizophrenia 1 (DISC1): association with schizophrenia, schizoaffective disorder, and bipolar disorder." in: American journal of human genetics, Vol. 75, Issue 5, pp. 862-72, (2004) (PubMed).
: "Evolutionary constraints on the Disrupted in Schizophrenia locus." in: Genomics, Vol. 81, Issue 1, pp. 67-77, (2003) (PubMed).
Synonyme und alternative Namen zu DISC1
disrupted in schizophrenia 1 (disc1), disrupted in schizophrenia 1 (DISC1), disrupted in schizophrenia 1 protein (LOC100580606), disrupted in schizophrenia 1 (Disc1), C1orf136, DISC1, SCZD9Bezeichner auf Proteinebene für DISC1
- disrupted in schizophrenia 1 protein
- disrupted in schizophrenia 1
- disrupted in schizophrenia 1 homolog
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