DIO2 Produkte
(Deiodinase, Iodothyronine, Type II (DIO2))
Kategorien
The protein encoded by this gene belongs to the iodothyronine deiodinase family. It activates thyroid hormone by converting the prohormone thyroxine (T4) by outer ring deiodination (ORD) to bioactive 3,3',5-triiodothyronine (T3). It is highly expressed in the thyroid, and may contribute significantly to the relative increase in thyroidal T3 production in patients with Graves disease and thyroid adenomas. This protein contains selenocysteine (Sec) residues encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
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Ausgewählte DIO2 Kategorien
DIO2 Antikörper
High quality antibodies with extensive validation data.
DIO2 ELISA Kits
Reliable ELISA kits for a wide range of species.
DIO2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene DIO2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, IHC (p), FACS
Validierungen
- (5)
Kat. Nr.
ABIN652664
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
ELISA, IHC, FACS, IF
Validierungen
- (1)
- (3)
Kat. Nr.
ABIN190862
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, IHC, IF
Validierungen
- (2)
Kat. Nr.
ABIN7173972
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene DIO2 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Competition ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6966307
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6955327
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6955328
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene DIO2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1351608
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3104665
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3120328
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren DIO2 Produkten
: "Prolonged inorganic arsenic exposure via drinking water impairs brown adipose tissue function in mice." in: The Science of the total environment, Vol. 668, pp. 310-317, (2019) (PubMed).: "Multipotent stem cell factor UGS148 is a marker for tanycytes in the adult hypothalamus." in: Molecular and cellular neurosciences, Vol. 65, pp. 21-30, (2015) (PubMed).
: "Reprogrammed Functional Brown Adipocytes Ameliorate Insulin Resistance and Dyslipidemia in Diet-Induced Obesity and Type 2 Diabetes." in: Stem cell reports, Vol. 5, Issue 4, pp. 569-81, (2015) (PubMed).
: "Treatment with thyroxine restores myelination and clinical recovery after intraventricular hemorrhage." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 44, pp. 17232-46, (2013) (PubMed).
: "Contributions of HIV infection in the hypothalamus and substance abuse/use to HPT dysregulation." in: Psychoneuroendocrinology, Vol. 36, Issue 5, pp. 710-9, (2011) (PubMed).
: "Ala92 type 2 deiodinase allele increases risk for the development of hypertension." in: Hypertension, Vol. 49, Issue 3, pp. 461-6, (2007) (PubMed).
Synonyme und alternative Namen zu DIO2
iodothyronine deiodinase 2 (DIO2), deiodinase, iodothyronine, type II (Dio2), iodothyronine deiodinase 2 (dio2), deiodinase, iodothyronine, type II (dio2), deiodinase, iodothyronine, type 2 L homeolog (dio2.L), deiodinase, iodothyronine, type 2 (dio2), iodothyronine deiodinase 2 (Dio2), type II iodothyronine deiodinase (LOC100861220), 5DII, 5dii, AI324267, cb684, D2, Deio2, DIO2, dio2-A, DIOII, SelY, sely, TXDI2, txdi2Bezeichner auf Proteinebene für DIO2
- thyroxine deiodinase, type II
- type 2 DI
- type 2 iodothyronine deiodinase
- type II iodothyronine deiodinase
- type-II 5'-deiodinase
- type-II 5'deiodinase
- iodothyronine type II deiodinase
- type-II 5' deiodinase
- deiodinase, iodothyronine, type 2
- D2
- 5DII
- DIOII
- deiodinase, iodothyronine, type II
- deiodinase 2
- type 2 deiodinase
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