DDR1 Produkte
(Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))
Kategorien
Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011].
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Ausgewählte DDR1 Kategorien
DDR1 Antikörper
High quality antibodies with extensive validation data.
DDR1 ELISA Kits
Reliable ELISA kits for a wide range of species.
DDR1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene DDR1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Rat
Applikation
WB, IHC (p), FACS
Validierungen
- (5)
Kat. Nr.
ABIN392014
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p), FACS, IF
Validierungen
- (5)
Kat. Nr.
ABIN391458
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, FACS, IF
Validierungen
- (7)
Kat. Nr.
ABIN3030734
Menge
0.4 mL
Datenblatt
Datenblatt
Empfohlene DDR1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validierungen
- (3)
Kat. Nr.
ABIN5526734
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validierungen
- (3)
Kat. Nr.
ABIN5526735
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6966389
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene DDR1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (4)
Kat. Nr.
ABIN7274460
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
HEK-293 Cells
Validierungen
- (2)
Kat. Nr.
ABIN7274462
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Insect cells (Sf21)
Validierungen
- (2)
Kat. Nr.
ABIN5570031
Menge
5 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren DDR1 Produkten
: "Targeting of DDR1 with antibody-drug conjugates has antitumor effects in a mouse model of colon carcinoma." in: Molecular oncology, (2019) (PubMed).: "Normal activation of discoidin domain receptor 1 mutants with disulfide cross-links, insertions, or deletions in the extracellular juxtamembrane region: mechanistic implications." in: The Journal of biological chemistry, Vol. 289, Issue 19, pp. 13565-74, (2014) (PubMed).
: "Activated hair follicle stem cells and Wnt/?-catenin signaling involve in pathnogenesis of sebaceous neoplasms." in: International journal of medical sciences, Vol. 11, Issue 10, pp. 1022-8, (2014) (PubMed).
: "A unique and potent protein binding nature of liposome containing polyethylenimine and polyethylene glycol: a nondisplaceable property." in: Biotechnology and bioengineering, Vol. 108, Issue 6, pp. 1318-27, (2011) (PubMed).
: "Novel markers for differentiation of lobular and ductal invasive breast carcinomas by laser microdissection and microarray analysis." in: BMC cancer, Vol. 7, pp. 55, (2007) (PubMed).
: "Sensing extracellular matrix: an update on discoidin domain receptor function." in: Cellular signalling, Vol. 18, Issue 8, pp. 1108-16, (2006) (PubMed).
: "Professional practice solutions.... How does a healthcare organization deal with conflicting directives between HCFA regulations and Joint Commission standards when obligated to abide by both?" in: Journal of AHIMA / American Health Information Management Association, Vol. 72, Issue 7, pp. 87-8, (2005) (PubMed).
: "Discoidin domain receptor (DDR) 1 and 2: collagen-activated tyrosine kinase receptors in the cornea." in: Experimental eye research, Vol. 72, Issue 1, pp. 87-92, (2001) (PubMed).
: "Discoidin domain receptor 1 (DDR1) signaling in PC12 cells: activation of juxtamembrane domains in PDGFR/DDR/TrkA chimeric receptors." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 14, Issue 7, pp. 973-81, (2000) (PubMed).
: "Discoidin domain receptor 1 functions in axon extension of cerebellar granule neurons." in: Genes & development, Vol. 14, Issue 17, pp. 2216-28, (2000) (PubMed).
Synonyme und alternative Namen zu DDR1
Discoidin domain receptor (Ddr), discoidin domain receptor family, member 1 (Ddr1), discoidin domain receptor tyrosine kinase 1 (DDR1), discoidin domain receptor tyrosine kinase 1 (Ddr1), 6030432F18, AI323681, Cak, CAK, CD167, CD167a, CG9488, CG9490, CG11573, CG13984, CG13985, CG33531, CT33540, DDR, Dmel\\CG33531, Dmel_CG13984, Drd1, EDDR1, HGK2, MCK10, Nep, NEP, NTRK4, PTK3, PTK3A, PTK3D, RTK6, TRKEBezeichner auf Proteinebene für DDR1
- CG33531-PA
- CG33531-PB
- Ddr-PA
- Ddr-PB
- discoidin domain receptor
- CD167 antigen-like family member A
- cell adhesion kinase
- discoidin receptor tyrosine kinase
- epithelial discoidin domain receptor 1
- epithelial discoidin domain-containing receptor 1
- protein-tyrosine kinase MPK-6
- tyrosine kinase DDR
- tyrosine-protein kinase CAK
- PTK3A protein tyrosine kinase 3A
- mammary carcinoma kinase 10
- neuroepithelial tyrosine kinase
- neurotrophic tyrosine kinase, receptor, type 4
- protein-tyrosine kinase RTK-6
- discoidin domain receptor family, member 1
- neurotrophic tyrosine kinase receptor type 4
- protein-tyrosine kinase 3
- protein-tyrosine kinase PTK-3
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