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DDC Produkte

(Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC))

Kategorien

The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jun 2011].

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Ausgewählte DDC Kategorien

DDC Antikörper

High quality antibodies with extensive validation data.

DDC ELISA Kits

Reliable ELISA kits for a wide range of species.

DDC Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene DDC Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC
Validierungen
  • (7)
Kat. Nr. ABIN1679510
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB, IF, IHC (p), FACS
Validierungen
  • (5)
Kat. Nr. ABIN651727
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (3)
Kat. Nr. ABIN7436294
Menge 100 μL
Datenblatt Datenblatt

Empfohlene DDC ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6955437
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6962232
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6999492
Menge 96 tests
Datenblatt Datenblatt

Empfohlene DDC Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7122700
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN667092
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1351264
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren DDC Produkten

Koblinger, Jean-Xavier, Sharma, Füzesi, Young, Eaton, Kwok, Bains, Whelan: "Optogenetic Activation of A11 Region Increases Motor Activity." in: Frontiers in neural circuits, Vol. 12, pp. 86, (2019) (PubMed).

Sharma, Kim, Mayr, Elliott, Whelan: "Parallel descending dopaminergic connectivity of A13 cells to the brainstem locomotor centers." in: Scientific reports, Vol. 8, Issue 1, pp. 7972, (2018) (PubMed).

Shimohata, Ishihara, Hattori, Miyamoto, Morishita, Ornthanalai, Raveau, Ebrahim, Amano, Yamada, Sago, Akiba, Mataga, Murphy, Miyakawa, Yamakawa: "Ts1Cje Down syndrome model mice exhibit environmental stimuli-triggered locomotor hyperactivity and sociability concurrent with increased flux through central dopamine and serotonin metabolism." in: Experimental neurology, Vol. 293, pp. 1-12, (2017) (PubMed).

Rivetti di Val Cervo, Romanov, Spigolon, Masini, Martín-Montañez, Toledo, La Manno, Feyder, Pifl, Ng, Sánchez, Linnarsson, Wernig, Harkany, Fisone, Arenas: "Induction of functional dopamine neurons from human astrocytes in vitro and mouse astrocytes in a Parkinson's disease model." in: Nature biotechnology, Vol. 35, Issue 5, pp. 444-452, (2017) (PubMed).

Jang, Park, Lee, Lee, Kim, Koh: "1,25-dyhydroxyvitamin D3 attenuates L-DOPA-induced neurotoxicity in neural stem cells." in: Molecular neurobiology, Vol. 51, Issue 2, pp. 558-70, (2015) (PubMed).

Hiramoto, Yamate, Kawanishi: "Detection of Dopa-positive cells in mouse ovaries in response to ocular exposure to ultraviolet B rays." in: Photodermatology, photoimmunology & photomedicine, (2014) (PubMed).

Koblinger, Füzesi, Ejdrygiewicz, Krajacic, Bains, Whelan: "Characterization of A11 neurons projecting to the spinal cord of mice." in: PLoS ONE, Vol. 9, Issue 10, pp. e109636, (2014) (PubMed).

San Sebastian, Kells, Bringas, Samaranch, Hadaczek, Ciesielska, Macayan, Pivirotto, Forsayeth, Osborne, Wright, Green, Heller, Bankiewicz: "SAFETY AND TOLERABILITY OF MRI-GUIDED INFUSION OF AAV2-hAADC INTO THE MID-BRAIN OF NON-HUMAN PRIMATE." in: Molecular therapy. Methods & clinical development, Vol. 3, (2014) (PubMed).

Blechingberg, Holm, Johansen, Børglum, Nielsen: "Aromatic l-amino acid decarboxylase expression profiling and isoform detection in the developing porcine brain." in: Brain research, Vol. 1308, pp. 1-13, (2009) (PubMed).

Voeller: "Attention-deficit hyperactivity disorder (ADHD)." in: Journal of child neurology, Vol. 19, Issue 10, pp. 798-814, (2004) (PubMed).

Synonyme und alternative Namen zu DDC

dopa decarboxylase (DDC), dopa decarboxylase (ddc), dopa decarboxylase (Ddc), Dopa-decarboxylase (Dvir\Ddc), dopa decarboxylase (aromatic L-amino acid decarboxylase) (DDC), Dopa decarboxylase (Ddc), dopa decarboxylase L homeolog (ddc.L), 5-HT, AADC, Aadc, CG10697, Ddc, DDC, ddc, DdcDm, DdcDv, Dmel\\CG10697, Dvir\\GJ17995, dvir_GLEANR_2561, fDDC, GJ17995, l(2)37Bl, l(2)37Ch, l(2)k02104, wu:fa56d05, wu:fd59h03, wu:fk20h01, zgc:65801, zgc:76929

Bezeichner auf Proteinebene für DDC

  • aromatic-L-amino-acid decarboxylase
  • L-aromatic dopa decarboxylase
  • aromatic-L-amino acid decarboxylase
  • aromatic amino acid decarboxylase
  • Ddc-PA
  • Dvir\\Ddc-PA
  • Dvir\\GJ17995-PA
  • GJ17995-PA
  • L-Dopa decarboxylase
  • AADC
  • aromatic L-amino acid decarboxylase
  • 3,4-Dihydroxyphenylalanine decarboxylase
  • CG10697-PB
  • CG10697-PC
  • CG10697-PD
  • Ddc-PB
  • Ddc-PC
  • Ddc-PD
  • dopa decarboxylase
  • dopa-decarboxylase
  • dopadecarboxylase
  • dopamine decarboxylase
  • transcription unit No. 3
  • dopa decarboxylase (aromatic L-amino acid decarboxylase)
  • Aromatic-L-amino-acid decarboxylase
  • aromatic-L-amino-acid decarboxylase-like
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