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COMP Proteine

(Cartilage Oligomeric Matrix Protein (COMP))
The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED). [provided by RefSeq, Jul 2008].

19 Treffer

COMP Spezies: Ratte Recombinant > 95 % (SDS-PAGE)
Pubmed 1 reference
Produktnummer ABIN1047991
 
COMP Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7505321
 
COMP Spezies: Human Wirt: HEK-293 Cells Recombinant > 90 % by SDS-PAGE.
Produktnummer ABIN7534407
 
COMP Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant SDS, WB, ELISA
Produktnummer ABIN7576295
 
COMP Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant SDS, WB, ELISA
Produktnummer ABIN7580569
 
COMP Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 97 % SDS, WB, Imm, PC
Produktnummer ABIN7393391
 
COMP Spezies: Ratte Wirt: Escherichia coli (E. coli) Recombinant > 90 % SDS, WB, Imm, PC
Produktnummer ABIN7421479
 
COMP Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, Imm, PC
Produktnummer ABIN7393394
 
COMP Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, Imm, PC
Produktnummer ABIN7402583
 
COMP Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, Imm, PC
Produktnummer ABIN7402586
 
COMP Spezies: Ratte Wirt: Escherichia coli (E. coli) Recombinant > 97 % SDS, WB, Imm, PC
Produktnummer ABIN7393397
 
COMP Spezies: Ratte Wirt: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, Imm, PC
Produktnummer ABIN7403273
 
COMP Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE. Active
Produktnummer ABIN7317991
 
COMP Spezies: Human Wirt: HEK-293 Cells Recombinant > 85% by SDS - PAGE SDS
Produktnummer ABIN7596455
 
COMP Spezies: Human Wirt: HEK-293 Cells Recombinant >88 % as determined by SDS-PAGE.
Produktnummer ABIN2180897
 
COMP Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, ELISA, IP
Produktnummer ABIN3008640
 
COMP Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2712452
 
COMP Spezies: Human Wirt: HEK-293 Cells Recombinant
Produktnummer ABIN1061972
 
COMP Spezies: Ratte Wirt: Hefe Recombinant > 90 % ELISA
Produktnummer ABIN7583901
 
  • Typ Protein
    • Protein
  • Anwendung
    • SDS-PAGE (SDS)
    • Western Blotting (WB)
    • Immunogen (Imm)
    • Positive Control (PC)
    • ELISA
    • Antibody Production (AbP)
    • Immunoprecipitation (IP)
    • Standard (STD)
  • Reaktivität
    • Human
    • Mouse
    • Rat
  • In Publikationen zitiert
  • Abbildungen verfügbar
  • Carrier free only
  • Wirt
    • Escherichia coli (E. coli)
    • HEK-293 Cells
    • Yeast
  • Bindungsspezifität
    • AA 21-757
    • AA 123-240
    • AA 20-755
    • AA 22-240
    • AA 235-423
    • AA 317-455
    • AA 35-179
    • AA 35-423
    • AA 40-180
    • AA 554-753
    • C-Term
  • Konjugat
    • His tag
    • Unkonjugiert
    • GST-His-Tag
    • Myc-DYKDDDDK Tag
  • Protein-Typ
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • Biologische Aktivität
    • Biologically Active
  • Hersteller
    • antibodies-online
    • ACROBiosystems
    • Abbexa
    • CUSABIO
    • ITSI-Biosciences
    • OriGene

Aktuelle Publikationen für unsere COMP Proteine

Wang, Chen, Xiang, Wu, Tang, Ma, Zhang: "ADAMTS7 degrades Comp to fuel BMP2-dependent osteogenic differentiation and ameliorate oncogenic potential in osteosarcomas." in: FEBS open bio, Vol. 10, Issue 9, pp. 1856-1867, (2020) (PubMed).

Spitznagel, Nitsche, Paulsson, Maurer, Zaucke: "Characterization of a pseudoachondroplasia-associated mutation (His587-->Arg) in the C-terminal, collagen-binding domain of cartilage oligomeric matrix protein (COMP)." in: The Biochemical journal, Vol. 377, Issue Pt 2, pp. 479-87, (2004) (PubMed).

Aliase für COMP Proteine

cartilage oligomeric matrix protein (COMP) Proteine
cartilage oligomeric matrix protein (sce3551) Proteine
cartilage oligomeric matrix protein (CJA_1292) Proteine
cartilage oligomeric matrix protein (Comp) Proteine
COMP Proteine
EDM1 Proteine
EPD1 Proteine
MED Proteine
PSACH Proteine
THBS5 Proteine
TSP5 Proteine
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